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4-Methoxychalcone

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Identification
Molecular formula
C10H10O
CAS number
35839-42-4
IUPAC name
1-(4-methoxyphenyl)prop-2-en-1-one
State
State

At room temperature, 4-Methoxychalcone appears as a solid. It maintains a crystalline structure that can be ground into a fine powder, exhibiting a yellowish or sometimes off-white color.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.00
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
224.26g/mol
Molar mass
224.2570g/mol
Density
1.0772g/cm3
Appearence

4-Methoxychalcone is an off-white solid. Its appearance can sometimes vary slightly depending on the presence of impurities, but it generally remains consistent as a pale or yellow-tinted crystalline powder.

Comment on solubility

Solubility of 1-(4-methoxyphenyl)prop-2-en-1-one

1-(4-methoxyphenyl)prop-2-en-1-one, commonly known as 4-methoxy-cinnamaldehyde, exhibits interesting solubility characteristics that impact its applications in various fields.

The solubility of this compound can be summarized as follows:

  • Solvent Compatibility: 1-(4-methoxyphenyl)prop-2-en-1-one is typically soluble in organic solvents such as ethanol, methanol, and chloroform.
  • Water Solubility: It demonstrates very low solubility in water due to its hydrophobic aromatic structure. This limited solubility in aqueous solutions can influence its bioavailability.
  • Temperature Effects: The solubility may increase with rising temperatures in organic solvents, which is common for many organic compounds. Therefore, heating can aid in dissolving the compound more effectively.

Furthermore, the presence of the -OCH3 (methoxy) group enhances its solubility in polar organic solvents while maintaining its relative insolubility in water. As a general rule, “Like dissolves like”—meaning polar compounds tend to dissolve well in polar solvents while nonpolar compounds are more soluble in nonpolar solvents.

In conclusion, understanding the solubility of 1-(4-methoxyphenyl)prop-2-en-1-one is essential for its utilization in various applications ranging from perfumery to pharmaceuticals.

Interesting facts

Interesting Facts about 1-(4-methoxyphenyl)prop-2-en-1-one

1-(4-methoxyphenyl)prop-2-en-1-one, commonly known in the scientific community for its unique structural attributes, presents a fascinating array of characteristics that pique the interest of chemists and researchers alike. Here are some compelling points about this compound:

  • Structural Diversity: The presence of both a methoxy group and an enone structure gives this compound versatility in reactivity, making it a valuable building block in organic synthesis.
  • Biological Activity: Compounds like 1-(4-methoxyphenyl)prop-2-en-1-one are often investigated for their potential biological properties, including anti-inflammatory, antioxidant, and anticancer activities.
  • Use in Dyes and Pigments: Due to its conjugated system, this compound can play a role in the design of dyes and pigments, contributing to the field of materials science.
  • Research Applications: Studies have shown that compounds structurally related to 1-(4-methoxyphenyl)prop-2-en-1-one can exhibit interesting pharmacological effects; hence, it's often used as a precursor in drug synthesis.
  • Inspiration from Nature: Some derivatives of this compound derive their inspiration from natural products, showcasing how nature often guides synthetic chemistry.

As a chemistry student, one might appreciate the compound's relevance in both theoretical studies and practical applications. The intriguing balance between its chemical properties and potential uses constantly invites fresh investigation, strengthening its place in the annals of organic chemistry.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” Compounds like 1-(4-methoxyphenyl)prop-2-en-1-one embody this ethos in their myriad of applications and ongoing research possibilities.

Synonyms
4'-Methoxyacrylophenone
7448-86-4
1'-Oxoestragole
p-Methoxyacrylophenone
p-Methoxyphenyl vinyl ketone
2-Propen-1-one, 1-(4-methoxyphenyl)-
ACRYLOPHENONE, 4'-METHOXY-
1-(4-Methoxyphenyl)-2-propen-1-one
BRN 2041093
UNII-A8M9Z5074S
A8M9Z5074S
DTXSID90225482
4-08-00-00887 (Beilstein Handbook Reference)
1-(P-METHOXYPHENYL)-2-PROPEN-1-ONE
DTXCID90147973
2-Propen-1-one, 1-(4-methoxyphenyl)-(9CI)
ymeswdpsfkmfnd-uhfffaoysa-n
1-(4-methoxyphenyl)prop-2-en-1-one
1-methoxy-4-acryloylbenzene
SCHEMBL546672
AKOS014316244
CS-0238731
EN300-200200
G65304
Q27273775