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4-Methoxyphenylpropargyl alcohol

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Identification
Molecular formula
C10H10O2
CAS number
39715-74-7
IUPAC name
1-(4-methoxyphenyl)prop-2-yn-1-ol
State
State

At room temperature, 4-Methoxyphenylpropargyl alcohol is a liquid.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
278.00
Boiling point (Kelvin)
551.15
General information
Molecular weight
150.10g/mol
Molar mass
148.1740g/mol
Density
1.0980g/cm3
Appearence

4-Methoxyphenylpropargyl alcohol is a clear, colorless liquid. It may have a faint odor typical of aromatic alcohols.

Comment on solubility

Solubility of 1-(4-Methoxyphenyl)prop-2-yn-1-ol

1-(4-Methoxyphenyl)prop-2-yn-1-ol is an organic compound characterized by its unique molecular structure. Its solubility properties are influenced by several factors:

  • Polarity: The presence of the hydroxyl group (-OH) typically enhances solubility in polar solvents, particularly water.
  • Functional Groups: The methoxy group (-OCH3) tends to increase solubility in organic solvents due to its hydrophobic character, making it somewhat soluble in non-polar environments.
  • Hydrogen Bonding: The ability of the hydroxyl group to form hydrogen bonds can significantly improve solubility in polar solvents.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in various solvents.

In essence, 1-(4-methoxyphenyl)prop-2-yn-1-ol exhibits moderate solubility in polar solvents, influenced by its hydroxyl and methoxy substituents. It is essential to consider these characteristics when predicting solubility behavior in different chemical environments:

"A compound's solubility is a key factor in its chemical reactivity and application in various fields."

Understanding the solubility of this compound can help in designing more effective synthesis and application methods in areas such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts About 1-(4-Methoxyphenyl)prop-2-yn-1-ol

1-(4-Methoxyphenyl)prop-2-yn-1-ol is a fascinating compound that falls under the category of propargyl alcohols, notable for their unique structural features and diverse chemical properties. Here are some intriguing aspects of this compound that highlight its significance in the field of chemistry:

  • Synthetic Versatility: The presence of the propargyl functional group enables this compound to participate in various synthetic reactions, making it a valuable building block in organic synthesis. It can be transformed into a variety of derivatives that may possess different biological activities.
  • Biological Relevance: Compounds like 1-(4-methoxyphenyl)prop-2-yn-1-ol have been explored for their potential pharmacological properties. Research indicates that many analogs of propargyl alcohol exhibit antiviral, anticancer, and anti-inflammatory activities.
  • Substituent Influence: The methoxy group (-OCH3) attached to the phenyl ring plays a crucial role in modulating the compound's reactivity and solubility. The electron-donating nature of the methoxy group can enhance nucleophilicity, facilitating various electrophilic substitution reactions.
  • Mechanistic Pathways: Understanding the reaction mechanisms involving this compound can provide insights into how variations in structure affect reactivity. Researchers often explore mechanistic pathways through techniques such as NMR spectroscopy and mass spectrometry.
  • Environmental Impact: Like many synthetic compounds, the assessment of the environmental impact of 1-(4-methoxyphenyl)prop-2-yn-1-ol is critical. Its degradation pathways and possible toxicity need to be addressed to ensure safe applications in various fields.

In summary, 1-(4-methoxyphenyl)prop-2-yn-1-ol exemplifies the connection between chemical structure and activity, serving as a source of inspiration for chemists exploring new compounds. As research continues, we may uncover even more about its potential applications and effects in both synthetic and biological realms.

Synonyms
19115-30-1
1'-Hydroxy-2',3'-dehydroestragole
OHDHE
alpha-Ethynyl-4-methoxybenzenemethanol
RefChem:915516
1-(4-methoxyphenyl)prop-2-yn-1-ol
1-(4-methoxyphenyl)-2-propyn-1-ol
MFCD01732756
BRN 2089996
Benzenemethanol, alpha-ethynyl-4-methoxy-
alpha-Ethynyl-p-methoxybenzyl alcohol
BENZYL ALCOHOL, alpha-ETHYNYL-p-METHOXY-
4-06-00-06456 (Beilstein Handbook Reference)
SCHEMBL6168264
DTXSID20940717
NJWJWMOLQUOFJR-UHFFFAOYSA-N
AC5064
AKOS006279322
HS-3661
1/'-hydroxy-2/',3/'-dehydroestragole
SY045242
3-hydroxy-3-(4-methoxyphenyl)-1-propyne
F8883-8265