Skip to main content

P-Methoxyphenylacetone

ADVERTISEMENT
Identification
Molecular formula
C10H12O2
CAS number
122-84-9
IUPAC name
1-(4-methoxyphenyl)propan-2-one
State
State

At room temperature, p-Methoxyphenylacetone is typically a liquid. Due to its low melting point, it remains in a liquid state under most ambient conditions.

Melting point (Celsius)
6.00
Melting point (Kelvin)
279.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
164.20g/mol
Molar mass
164.2040g/mol
Density
1.0350g/cm3
Appearence

P-Methoxyphenylacetone is a colorless to pale yellow liquid. It is often characterized by its aromatic odor due to the methoxyphenyl group attached to the ketone structure.

Comment on solubility

Solubility of 1-(4-methoxyphenyl)propan-2-one

The solubility of 1-(4-methoxyphenyl)propan-2-one, commonly known as butyrophenone, is influenced by its molecular structure and the nature of its substituents. This compound exhibits moderate solubility in various solvents, which can be summarized as follows:

  • Polar solvents: 1-(4-methoxyphenyl)propan-2-one tends to be less soluble in highly polar solvents such as water due to its hydrophobic nature, primarily driven by the aromatic ring structure.
  • Non-polar solvents: It shows significant solubility in non-polar organic solvents like hexane and ether because of its hydrophobic properties.
  • Intermediate solvents: In solvents like ethanol and acetone, it displays variable solubility, often tending towards more soluble behaviors due to the presence of the methoxy group, which can engage in hydrogen bonding.

As a result, one might say that the solubility of 1-(4-methoxyphenyl)propan-2-one can be categorized as:

  1. Higher solubility: in non-polar organic solvents
  2. Moderate solubility: in intermediate polar solvents
  3. Low solubility: in polar solvents like water

In practical applications, understanding the solubility profile is crucial for determining the feasibility of extraction, formulation, and synthesis processes involving this compound.

Interesting facts

Interesting Facts about 1-(4-methoxyphenyl)propan-2-one

1-(4-methoxyphenyl)propan-2-one, also known as 4-Methoxyacetophenone, is a fascinating compound that finds its applications across various fields, particularly in organic synthesis and the fragrance industry.

Applications

  • Fragrance Industry: This compound is utilized as a fragrant ingredient in perfumes and personal care products due to its sweet, floral aroma.
  • Intermediate in Organic Synthesis: It is a valuable intermediate in the synthesis of other organic compounds, enabling the production of more complex chemical structures.
  • Flavoring Agent: Beyond its scent, it is also used as a flavoring agent in some food products.

Reactivity and Chemical Behavior

The chemical structure of 1-(4-methoxyphenyl)propan-2-one allows it to undergo various chemical reactions, making it a versatile component in laboratories. Notably, its ketone functional group plays a crucial role in:

  • Nucleophilic Additions: This compound can participate in nucleophilic addition reactions, leading to the formation of alcohols or other derivatives.
  • Aldol Reactions: It can act as both a nucleophile and an electrophile, paving the way for aldol reactions that create larger molecular frameworks.

Safety and Handling

When working with 1-(4-methoxyphenyl)propan-2-one, it is essential to follow safety protocols as with any chemical. Here are some key points:

  • Use appropriate personal protective equipment (PPE) such as gloves and goggles.
  • Handle under a fume hood to avoid inhalation of vapors.

In conclusion, 1-(4-methoxyphenyl)propan-2-one stands out as a compound of interest due to its aromatic properties and versatility in chemical synthesis. Whether in the synthesis lab or the fragrance industry, its applications are as diverse as the methods used to create it. As with many organic compounds, understanding its chemistry helps unveil the intricate world of molecular interactions and practical applications.

Synonyms
4-Methoxyphenylacetone
122-84-9
2-Propanone, 1-(4-methoxyphenyl)-
1-(4-methoxyphenyl)propan-2-one
Anisketone
p-Acetonylanisole
Anisyl methyl ketone
1-(4-Methoxyphenyl)-2-propanone
p-Methoxyphenylacetone
Anisic ketone
1-(p-Methoxyphenyl)-2-propanone
4-Methoxybenzyl methyl ketone
p-Methoxybenzyl methyl ketone
1-(4-Methoxyphenyl)acetone
1-(p-Anisyl)-2-propanone
4'-Methoxyphenyl-2-propanone
p-Anisylactone
2-PROPANONE, 1-(p-METHOXYPHENYL)-
P-ANISYLACETONE
2-Propanone, (p-methoxyphenyl)-
(p-Methoxyphenyl)-2-propanone
FEMA No. 2674
NSC 22983
para-anisyl methyl ketone
EINECS 204-578-7
6XYW3YJJ33
BRN 2044332
AI3-37913
1-(p-Methoxyphenyl)-2-propanone (natural)
ANISYLMETHYL KETONE
NSC-22983
NSC-46101
DTXSID9059545
4-08-00-00460 (Beilstein Handbook Reference)
1-(P-METHOXYPHENYL)-2-PROPANONE [FHFI]
MEBEVERINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
MEBEVERINE HYDROCHLORIDE IMPURITY A (EP IMPURITY)
RefChem:428221
DTXCID2033732
204-578-7
InChI=1/C10H12O2/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6H,7H2,1-2H
MFCD00008773
1-(4-METHOXY-PHENYL)-PROPAN-2-ONE
UNII-6XYW3YJJ33
Anisylaceton
Anisyl ketone
Anisylacetone?
4-Acetonylanisole
p-methoxy phenylacetone
4-Methoxyphenoxyacetone
4-methoxy phenylacetone
4-methoxyphenyl acetone
(p-methoxyphenyl)acetone
4-Methoxy phenyl acetone
SCHEMBL48525
ghl.PD_Mitscher_leg0.658
4-methoxyphenyl-propan-2-one
1-(4-Methoxyphenyl)acetone #
CHEMBL473366
SCHEMBL28037425
SCHEMBL28072691
4-Methoxyphenylacetone, >=97%
FEMA 2674
CHEBI:180410
1-(4'-methoxyphenyl)-2-propanone
1-(4-methoxy-phenyl)propan-2-one
1-(4-methoxyphenyl)-propan-2-one
NSC22983
NSC46101
1-(4Methoxy-phenyl)-propan-2-one
BBL027728
SBB058529
STL146340
AKOS000119418
AB00957
AC-5625
CS-W002045
FM25338
3-(4-METHOXYPHENYL)-2-PROPANONE
AS-12912
PD150881
SY001528
1-(p-Methoxyphenyl)-2-propanone, >=97%
DB-003502
M0675
NS00011990
ST50406450
F003622
Q27265692
F0001-0359
915232-26-7