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4'-tert-Butylacetophenone

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Identification
Molecular formula
C12H16O
CAS number
943-27-1
IUPAC name
1-(4-tert-butylphenyl)ethanone
State
State

At room temperature, 4'-tert-Butylacetophenone exists as a solid. Its relatively high melting point compared to many organic compounds of similar size contributes to its solid state under standard conditions.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.15
Boiling point (Celsius)
262.00
Boiling point (Kelvin)
535.15
General information
Molecular weight
176.27g/mol
Molar mass
176.2660g/mol
Density
0.9815g/cm3
Appearence

4'-tert-Butylacetophenone is a white to off-white crystalline solid. It is characterized by its tert-butyl functional group attached to the para position of the phenyl ring, giving it a distinctive structural appearance.

Comment on solubility

Solubility of 1-(4-tert-butylphenyl)ethanone

1-(4-tert-butylphenyl)ethanone, a compound known for its unique structure, displays interesting solubility properties that are noteworthy:

  • Solvent Dependence: This compound is generally soluble in organic solvents such as ether, chloroform, and acetone.
  • Hydrophilicity: It exhibits low solubility in water, which can be attributed to the presence of the hydrophobic tert-butyl group.
  • Temperature Influence: Solubility can increase with temperature, which is common for many organic compounds.
  • Concentration Effects: As the concentration of 1-(4-tert-butylphenyl)ethanone increases, saturation limits may be observed in specific solvents.

In general, understanding the solubility of this compound is crucial for applications in various fields, especially in organic synthesis where the choice of solvent can significantly affect reaction outcomes. As a rule of thumb, “like dissolves like,” which means that non-polar solvents are ideal for dissolving 1-(4-tert-butylphenyl)ethanone effectively.

Interesting facts

1-(4-tert-butylphenyl)ethanone: An Overview

1-(4-tert-butylphenyl)ethanone, commonly referred to as a ketone derivative, showcases a fascinating interplay of chemical properties and potential applications. This compound is of particular interest in organic chemistry due to its unique structural features and functional capabilities.

Significant Properties

  • Functional Group: As a ketone, it possesses a carbonyl group (C=O), which is pivotal in many biochemical processes.
  • Substituents: The tert-butyl group enhances the molecule's steric bulk, influencing reactivity and stability.
  • Aromatic System: The phenyl ring contributes to the overall electron distribution, affecting the compound's reactivity and solubility in organic solvents.

Potential Applications

This versatile compound can serve various roles in synthesis and industry:

  • Intermediate in Synthesis: It can act as a building block for more complex molecules in pharmaceuticals or agrochemicals.
  • Research Tool: Used in studies that explore ketone reactivity and its interactions with other organic compounds.
  • Flavor and Fragrance: Due to its structure, it may contribute to the development of specific aromas or flavors.

Chemical Exploration

As a compound of interest in chemical research, 1-(4-tert-butylphenyl)ethanone can inspire discussions about:

  • The mechanisms of ketone reactions, particularly nucleophilic additions.
  • Comparative analysis of branched versus linear alkyl substituents on reaction rates.
  • The role of steric hindrance in organic reactions and how it influences selectivity.

In conclusion, exploring 1-(4-tert-butylphenyl)ethanone offers not only practical implications in synthesis but also deep insights into the fundamental principles that govern organic reactions. It’s a wonderful example of how a seemingly simple compound can play a pivotal role in the vast world of chemistry.

Synonyms
4'-tert-Butylacetophenone
943-27-1
4-tert-Butylacetophenone
p-tert-Butylacetophenone
Acetophenone, 4'-tert-butyl-
Ethanone, 1-[4-(1,1-dimethylethyl)phenyl]-
JAH8J5D78Y
4-TERT-BUTYLPHENYL METHYL KETONE
NSC 826
NSC-826
p-tert-Butylacetylbenzene
Ethanone, 1-(4-(1,1-dimethylethyl)phenyl)-
EINECS 213-399-3
1-((1,1-Dimethylethyl)phenyl)ethanone
Ethanone, 1-((1,1-dimethylethyl)phenyl)-
Ethanone, 1-[(1,1-dimethylethyl)phenyl]-
DTXSID4061337
DTXCID0048929
Acetophenone, 4'-tert-butyl-(8CI)
213-399-3
1-(4-tert-Butylphenyl)ethanone
1-(4-(tert-Butyl)phenyl)ethanone
1-(4-tert-butyl-phenyl)-ethanone
MFCD00017256
1-(4-tert-butylphenyl)ethan-1-one
4 inverted exclamation marka-tert-Butylacetophenone
4'-(tert-Butyl)acetophenone
1-[4-(1,1-Dimethylethyl)phenyl]ethanone
Ebastine Impurity B (4'-tert-Butylacetophenone)
43133-94-4
4-tert-Butylphenyl methyl ketone; 4'-tert-Butylacetophenone; NSC 826; p-tert-Butylacetophenone
NSC826
Ebastine Imp. B (EP); 1-[4-(1,1-Dimethylethyl)phenyl]ethanone; Ebastine Related Compound B; Ebastine Impurity B
4'-t-Butylacetophenone
4'-tert.butylacetophenone
p-tert.-Butyl-acetophenon
UNII-JAH8J5D78Y
4\'-tert-Butylacetophenone
SCHEMBL397829
P-TERT-BUTYL ACETOPHENONE
UYFJYGWNYQCHOB-UHFFFAOYSA-
4'-tert-Butylacetophenone, 97%
Ethanone,1-dimethylethyl)phenyl]-
1-(4-tert-Butylphenyl)ethanone #
ALBB-002896
HY-Y0621
STR02739
BBL036992
STK501068
4'-(TERT-BUTYL)-ACETOPHENONE
AKOS000120891
CS-W020585
FB19505
FS-1037
NCGC00339231-01
PD065626
SY017114
DB-006904
NS00012024
EN300-18619
AB00633280-03
4 inverted exclamation mark -tert-Butylacetophenone
Q63395335
Z85956680
F0001-2263
InChI=1/C12H16O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-8H,1-4H3
1-[4-(1,1-Dimethylethyl)phenyl]ethanone;1-(4-tert-Butylphenyl)ethanone;4-tert-Butylphenyl methyl ketone