Interesting facts
Interesting Facts about 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
This complex organic compound belongs to a class known as piperidines, which are six-membered ring structures containing one nitrogen atom. Due to its intricate structure, this compound presents several fascinating features that make it noteworthy in the field of chemistry:
- Molecular Diversity: This compound showcases a remarkable degree of molecular diversity, incorporating multiple functional groups such as fluorophenyl and trifluoromethyl moieties. The presence of these substituents can significantly influence the compound's chemical behavior and interactions.
- Potential Applications: Compounds like this one are of interest in medicinal chemistry and pharmaceutical development. The unique structure could be optimized for use as a therapeutic agent, particularly due to the presence of various functional groups that can enhance biological activity.
- Structure-Activity Relationship (SAR): The extensive modifications in the phenyl rings and the piperidine core provide an excellent platform for studying the structure-activity relationship. Understanding how these structural components affect biological properties could lead to new discoveries in drug design.
- Fluorine Substitution: The incorporation of fluorine atoms is known to improve the metabolic stability of organic compounds. This could potentially lead to a compound that exhibits prolonged activity within biological systems.
In summary, the compound 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol stands out in the realm of synthetic organic chemistry. Its complexity invites further research into its properties and potential applications, which could contribute to advancements in various scientific fields.
Synonyms
PENFLURIDOL
26864-56-2
Semap
Penfluridolum
McN-JR-16,341
R-16341
DTXSID5049021
R 16341
NSC-759179
25TLU22Q8H
MCN-JR-16341
4-Piperidinol, 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)-
R 16,341
DTXCID6028947
R16341
4-Piperidinol, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-
RefChem:859405
N05AG03
248-074-5
1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
C28H27ClF5NO
TLP-607
MFCD00866714
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
Micefal
1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
4-Piperidinol,1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-
CHEMBL47050
NCGC00165865-01
A1L60
Penfluridolum [INN-Latin]
1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol
CAS-26864-56-2
EINECS 248-074-5
BRN 1558826
UNII-25TLU22Q8H
Longoperidol
Penfluridol [USAN:INN:BAN]
1-(4,4-BIS(P-FLUOROPHENYL)BUTYL)-4-(4-CHLORO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-4-PIPERIDINOL
1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-m-tolyl)-4-piperidinol
Semap (TN)
Penfluridol (Standard)
PENFLURIDOL [MI]
PENFLURIDOL [INN]
PENFLURIDOL [JAN]
Penfluridol (USAN/INN)
PENFLURIDOL [USAN]
PENFLURIDOL [MART.]
SCHEMBL93939
PENFLURIDOL [WHO-DD]
1-(4,4-Bis(p-fluorophenyl)butyl)-4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-4-piperidinol
5-21-02-00409 (Beilstein Handbook Reference)
MLS004774011
orb1309759
SCHEMBL30546621
CHEBI:92278
HY-B1077R
GLXC-06132
HMS3264L13
HMS3652G22
HMS5082M20
Pharmakon1600-01505691
BCP03695
HY-B1077
MSK10525
Tox21_113546
BDBM50026066
NSC759179
PDSP1_000470
PDSP2_000468
AKOS005065828
Tox21_113546_1
BCP9000014
CCG-269878
CS-4633
DB13791
FP37146
KS-5104
NSC 759179
Penfluridol, >=97% (HPLC), powder
NCGC00165865-02
NCGC00165865-03
4-Piperidinol, 1-(4,4-bis(p-fluorophenyl)butyl)-4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-
4-Piperidinol, 4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-1-(4,4-bis(p-fluorophenyl)butyl)-
AC-15413
SMR003500704
SY057974
BCP0726000159
SBI-0206898.P001
DB-017683
NS00002358
P2076
S4151
SW219540-1
D02630
AB01566919_01
864P562
A818637
L001145
SR-05000001779
Q2149707
SR-05000001779-1
BRD-K15409150-001-01-7
BRD-K15409150-001-05-8
BRD-K15409150-001-07-4
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloranyl-3-(trifluoromethyl)phenyl]piperidin-4-ol
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-piperidin-4-ol
1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol
1-[4,4-Bis(p-flurophenyl)butyl]-4-(4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-m-tolyl)-4-piperidinol
4-Piperidinol, 4-(4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-m-tolyl)-1-(4,4-bis(p-fluorophenyl)butyl)-
PENFLURIDOL1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol
Solubility of 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
The solubility of 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol can be characterized as relatively complex due to its unique molecular structure. Understanding its solubility properties is crucial for practical applications and chemical interactions.
Key Considerations for Solubility:
In summary, while the solubility of this compound is not straightforward, it is clear that the characteristics of its molecular structure and the choice of solvent play significant roles. Further empirical studies would provide valuable insights into specific solubility attributes.