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Xylometazoline hydrochloride

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Identification
Molecular formula
C16H25ClN2
CAS number
1218-35-5
IUPAC name
1-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-3-ethyl-indole;chloride
State
State

At room temperature, Xylometazoline hydrochloride is a solid.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.00
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.00
General information
Molecular weight
266.80g/mol
Molar mass
266.7980g/mol
Density
1.3000g/cm3
Appearence

Xylometazoline hydrochloride appears as a white or light yellow crystalline powder.

Comment on solubility

Solubility of 1-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-3-ethyl-indole;chloride

The solubility of 1-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-3-ethyl-indole;chloride is influenced by several factors that are worth discussing:

  • Polarity: The presence of the imidazolium cation contributes to increased polarity, which may enhance its solubility in polar solvents such as water.
  • Chloride Ion: The chloride part of the compound typically enhances solubility in aqueous solutions due to the ion-dipole interactions.
  • Hydrogen Bonding: The ability of the imidazole ring to form hydrogen bonds further suggests it may dissolve well in protic solvents.

However, it’s essential to consider specific solubility characteristics:

  • In water, this compound may exhibit moderate to high solubility due to its ionic nature.
  • In organic solvents, solubility can vary significantly and may be lower compared to its performance in polar solvents.

In conclusion, while the solubility of 1-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-3-ethyl-indole;chloride can benefit from its ionic structure and hydrogen bonding capabilities, further empirical data would be needed to provide definitive solubility parameters across different solvents. Understanding these interactions can greatly influence its applications in various chemical processes.

Interesting facts

Interesting Facts about 1-(4,5-Dihydro-1H-imidazol-1-ium-2-ylmethyl)-3-ethyl-indole;chloride

This compound is a fascinating member of the indole family, which has garnered attention in various fields, including medicinal chemistry and material science. Here are some intriguing insights:

  • Structural Complexity: The compound features a unique structure that includes an indole moiety fused with a 4,5-dihydro-1H-imidazolium unit. This structural diversity enhances its potential for varied interactions within biological systems.
  • Biological Relevance: Compounds related to indoles are often found in nature and have been shown to display significant biological activities. Indole derivatives can act as neurotransmitter precursors and have roles in plant growth, making them crucial in both biological and ecological contexts.
  • Pharmacological Potential: Research suggests that similar compounds can exhibit anti-inflammatory, anti-cancer, and anti-microbial properties. The presence of ammonium ions can influence the solubility and absorption in biological systems, making this compound a target for drug development.
  • Versatile Applications: Beyond medicinal applications, derivatives of indole and imidazole can serve as building blocks in organic synthesis and materials science, as they may exhibit interesting electronic or optical properties.
  • Research Opportunities: The unique properties of this compound open avenues for further research. Studies could investigate its interactions with various biological targets or explore its use in synthetic methodologies.

In conclusion, this compound exemplifies the rich potential within organic chemistry, where complex structures not only invite curiosity but also promise significant applications across multiple scientific domains. As Plato once said, "The beginning of wisdom is the definition of terms," which rings true when exploring the intricate world of chemical compounds and their myriad possibilities.

Synonyms
WIN 29148A
3-Ethyl-1-(2-imidazolin-2-ylmethyl)indole hydrochloride
22683-22-3
INDOLE, 3-ETHYL-1-(2-IMIDAZOLIN-2-YLMETHYL)-, MONOHYDROCHLORIDE
RefChem:349260