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LY-293284

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Identification
Molecular formula
C23H32N2O2S
CAS number
135444-77-2
IUPAC name
1-(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-N,N-dimethyl-methanesulfonamide
State
State

At room temperature, LY-293284 is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.20
Boiling point (Celsius)
172.50
Boiling point (Kelvin)
445.70
General information
Molecular weight
388.58g/mol
Molar mass
388.5600g/mol
Density
1.2900g/cm3
Appearence

LY-293284 is typically observed as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-N,N-dimethyl-methanesulfonamide

The solubility of a compound can greatly influence its effectiveness and behavior in various applications. For the compound 1-(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-N,N-dimethyl-methanesulfonamide (C23H32N2O2S), several factors can determine its solubility:

  • Polarity: The presence of methanesulfonamide groups can increase solubility in polar solvents due to interactions with water.
  • Hydrophobicity: The large aromatic and hydrophobic portion of the molecule may decrease solubility in exclusively polar solvents.
  • Temperature: Higher temperatures often increase solubility for many compounds, which may also be applicable here.
  • pH Levels: The ionization of the sulfonamide group can alter solubility based on the pH of the solution.

In summary, understanding the interplay of these factors is critical. The solubility of this compound is likely to be moderate in polar solvents, while less effective in non-polar environments. Therefore, when working with this molecule in practical applications, one should consider testing its solubility under various conditions for optimal results.

Interesting facts

Interesting Facts about 1-(4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)-N,N-dimethyl-methanesulfonamide

This compound is a remarkable member of the indole family of alicyclic amines, displaying unique structural features that contribute to its potential applications in various fields, particularly in medicinal chemistry. It embodies a union of nitrogen-rich heterocyclic rings and a sulfonamide group, making it a fascinating subject for research and exploration.

Structural Highlights:

  • Heterocyclic Framework: The compound contains a complex indoloquinoline structure which is known for its diverse pharmacological activities.
  • Sulfonamide Group: This group is often associated with antibacterial properties, which adds to the compound's potential therapeutic uses.
  • Dimethyl Substituents: The presence of multiple methyl groups enhances the lipophilicity of the compound, which may influence its bioavailability.

In the realm of medicinal applications, compounds with similar structural motifs have been noted for their capabilities in:

  • Treatment of cancer due to their ability to intercalate into DNA
  • Exhibiting antimicrobial properties that can inhibit bacterial growth
  • Serving as potential antidepressants or in the modulation of serotonin pathways

As a scientist or a chemistry student diving into the world of organic compounds, understanding the interactions and transformations of such molecules is crucial. This compound exemplifies the interconnectedness of structural chemistry, pharmacology, and the potential for future therapeutic developments.

In the words of renowned chemist Robert H. Grubbs, "Chemistry is the science of change," and this compound illustrates that principle beautifully through its intricate structure and versatile functionalities.

Synonyms
[3H]mesulergine
(3H)mesulergine
1-{6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraen-4-yl}-N,N-dimethylmethanesulfonamide
1-(6,11-dimethyl-6,11-diazatetracyclo(7.6.1.0^(2,7).0^(12,16))hexadeca-1(16),9,12,14-tetraen-4-yl)-N,N-dimethylmethanesulfonamide
GTPL232
SCHEMBL11890532