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5-Bromo-DMT

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Identification
Molecular formula
C12H15BrN2
CAS number
22137-87-3
IUPAC name
1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine
State
State

At room temperature, 5-Bromo-DMT is typically found in a solid state, preferably as a crystalline powder. It is not very volatile and remains stable under standard conditions.

Melting point (Celsius)
67.50
Melting point (Kelvin)
340.70
Boiling point (Celsius)
349.30
Boiling point (Kelvin)
622.40
General information
Molecular weight
268.17g/mol
Molar mass
268.1540g/mol
Density
1.5000g/cm3
Appearence

5-Bromo-DMT typically appears as a crystalline solid, often off-white to pale yellow in color. It may vary slightly depending on the purity and the specific conditions under which it was synthesized.

Comment on solubility

Solubility of 1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine

Understanding the solubility of 1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine is crucial for its application in various chemical environments. This compound, with a complex structure, presents interesting solubility characteristics:

  • Polar vs. Nonpolar Solvent: The presence of both the bromo group and the amine functionality often suggests that the compound may exhibit increased solubility in polar solvents such as water and methanol, while showing limited solubility in nonpolar solvents like hexane.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amine group enhances its interaction with polar solvents, facilitating solubility.
  • Temperature Dependency: Increasing the temperature can often improve solubility, particularly for organic compounds. This might apply here as well.
  • pH Sensitivity: The solubility may also vary with pH; under acidic conditions, the amine group can become protonated, potentially improving solubility in aqueous solutions.

Due to these factors, the solubility profile of this compound may reveal itself as:

  1. Highly soluble in polar solvents.
  2. Moderately soluble in organic solvents, depending on structure variability and interaction.

In conclusion, studying the solubility of this compound is like embarking on a chemical adventure, filled with unpredictabilities influenced by polarity, temperature, and pH.

Interesting facts

Interesting Facts about 1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine

1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine, a compound from the indole family, has garnered interest in the fields of chemistry and pharmacology due to its intriguing structure and potential applications. Here are some compelling points about this compound:

  • Unique Structure: The presence of both a bromine atom and a dimethylamine group in the same molecule contributes to its complexity and diverse reactivity. This structure allows for various derivatives to be synthesized, enhancing its versatility.
  • Indole Derivative: Indole compounds are known for their biological significance. They often serve as core structures in pharmaceuticals and natural products. The bromination at the 5-position can significantly influence the compound's biological activity and interactions with biological targets.
  • Potential Pharmacological Properties: Research on similar compounds has shown that indole derivatives exhibit a range of activities, including anti-inflammatory, antimicrobial, and antitumor effects. This compound’s unique configuration may offer new insights into the development of therapeutic agents.
  • Applications in Research: Due to its specific properties, this compound may be utilized in various research fields, including medicinal chemistry, materials science, and organic synthesis. Its ability to act as a building block for more complex molecules makes it a valuable compound in synthetic methodologies.
  • Chemical Stability: The stability of the bromine substituent can lead to interesting reactions under specific conditions, allowing chemists to explore different reaction pathways and mechanisms, a fact that is crucial for drug development and industrial chemistry.

As research progresses, compounds like 1-(5-bromo-1H-indol-3-yl)-N,N-dimethyl-methanamine may unveil further possibilities in drug discovery and organic synthesis, showcasing the endless potential that organic chemistry holds for addressing modern challenges.

Synonyms
5-Bromogramine
INDOLE, 5-BROMO-3-(DIMETHYLAMINO)METHYL-
NSC 73386
BRN 0160259
1H-Indole-3-methanamine, 5-bromo-N,N-dimethyl-
DTXSID80232120
4-22-00-04316 (Beilstein Handbook Reference)
DTXCID80154611
1H-Indole-3-methanamine, 5-bromo-N,N-dimethyl-(9CI)
624-136-0
830-93-3
1-(5-bromo-1H-indol-3-yl)-N,N-dimethylmethanamine
MFCD00055980
[(5-Bromo-1H-Indol-3-Yl)Methyl]Dimethylamine
5-bromogramine crystalline
5-bromo-3-(dimethylaminomethyl)indole
NSC73386
5-Bromo-N,N-dimethyl-1H-Indole-3-methanamine
SCHEMBL1196680
CHEMBL1253697
FSERHDPEOFYMMK-UHFFFAOYSA-N
NSC-73386
AKOS005259245
HY-W142374
AC-27826
BS-22636
DB-018633
CS-0204422
(5-bromo-1H-indol-3-ylmethyl)-dimethyl-amine
A19211
EN300-203559
(5-bromo-1H-indol-3-yl)-N,N-dimethylmethanamine
Z1269196757