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5-Fluoro-DMT

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Identification
Molecular formula
C12H15FN2
CAS number
not known
IUPAC name
1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine
State
State

At room temperature, 5-Fluoro-DMT is typically in a solid state. It may be handled as a hydrochloride salt, which is common for amine compounds to increase aqueous solubility and stability.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
190.24g/mol
Molar mass
190.2390g/mol
Density
1.2000g/cm3
Appearence

5-Fluoro-DMT typically appears as a white to off-white crystalline solid, although its exact appearance can vary depending on the purity and form (e.g., salt or freebase) of the compound.

Comment on solubility

Solubility of 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine

The solubility of 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine can be influenced by several factors, including its molecular structure and the presence of functional groups. Generally, this compound exhibits solubility in a variety of organic solvents, which can be characterized as follows:

  • Apolar solvents: The compound may show limited solubility in non-polar solvents due to its polar functional groups.
  • Polar aprotic solvents: Substances like dimethyl sulfoxide (DMSO) or acetone may dissolve this compound more readily due to their ability to interact with polar regions.
  • Water solubility: While the presence of the dimethylamino group suggests possible solubility in water, large hydrophobic regions can limit solubility.

As a general rule, the solubility of organics in water can often be predicted by the “like dissolves like” principle. For our compound, the following aspects can be highlighted:

  • Hydrogen bonding capacity with water may enhance its solubility.
  • However, the bulky indole structure could impose steric hindrance, adversely affecting water solubility.

In summary, while 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine may find its niche within certain solvents, its solubility profile is primarily determined by its structural characteristics and the nature of the solvent used.

Interesting facts

Exploring 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine

1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine is a fascinating compound with a range of interesting attributes, particularly in the field of medicinal chemistry. As a member of the indole family, this compound plays a significant role in drug discovery and development. Here are some key highlights about it:

  • Indole Derivative: The presence of the indole structure is noteworthy, as indoles are known for their occurrence in various natural compounds and have biological significance.
  • Fluorine Substitution: The incorporation of fluorine in its structure enhances the compound's lipophilicity, which can influence its bioavailability and interactions within biological systems.
  • Psychoactive Properties: Compounds related to indole, especially those with modifications like dimethylamines, have been studied for their psychoactive properties, making them of interest in neurology and pharmacology.
  • Pharmaceutical Research: This compound may serve as a lead compound in the synthesis of new therapeutic agents, particularly for treating mental health disorders, due to its structural similarity to known bioactive molecules.

In the words of a noted chemist, "The indole scaffold has provided a plethora of biologically active compounds, and modifications like those in 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine could pave the way for the next breakthrough in pharmaceutical science."

Overall, the exploration of 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethyl-methanamine not only highlights the significance of structure-activity relationships in medicinal chemistry but also encourages future research into its potential applications and effects.

Synonyms
5-Fluorogramine
343-90-8
1-(5-fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine
3-((Dimethylamino)methyl)-5-fluoroindole
INDOLE, 3-(DIMETHYLAMINO)METHYL-5-FLUORO-
NSC 88621
BRN 0160256
AM52C35PV7
[(5-fluoro-1H-indol-3-yl)methyl]dimethylamine
NSC-88621
1H-Indole-3-methanamine, 5-fluoro-N,N-dimethyl-
DTXSID40187864
5-Fluoro-N,N-dimethyl-1H-indole-3-methanamine
5-22-10-00034 (Beilstein Handbook Reference)
NSC88621
3-dimethylaminomethyl-5-fluoroindole
MFCD00022731
3-(Dimethylaminomethyl)-5-fluoro-1H-indole
UNII-AM52C35PV7
SCHEMBL3216581
DTXCID00110355
QNCNSISRJMCGPK-UHFFFAOYSA-N
STL220630
AKOS006227760
5-fluoro-3-(dimethylaminomethyl)indole
CS-W021243
FF42157
FS-1254
5-fluoro-3-dimethylaminomethyl-1h-indole
AC-27828
DB-048614
1H-Indole-3-methanamine, 5-fluoro-N,N-dimethyl-(9CI)
1-(5-Fluoro-1H-indol-3-yl)-N pound notN-dimethylmethanamine