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5-Fluoro-DMT

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Identification
Molecular formula
C11H13FN2
CAS number
22163-13-1
IUPAC name
1-(5-fluoro-1H-indol-3-yl)propan-2-amine
State
State

At room temperature, 5-Fluoro-DMT is typically a solid. Its precise state can vary slightly with different formulations, but it is generally encountered as a crystalline powder.

Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
194.24g/mol
Molar mass
194.2420g/mol
Density
1.2200g/cm3
Appearence

5-Fluoro-DMT usually appears as a crystalline solid. The crystalline form is typically white or off-white, although slight variations in color may occur depending on the synthesis process and purity of the sample. It may also be available in powder form.

Comment on solubility

Solubility of 1-(5-fluoro-1H-indol-3-yl)propan-2-amine

The solubility of 1-(5-fluoro-1H-indol-3-yl)propan-2-amine can be influenced by several factors including its molecular structure and the chemical environment. Generally, this compound is expected to exhibit variable solubility characteristics, which can be summarized as follows:

  • Polarity: The presence of the indole ring and an amine functional group likely contributes to the compound's overall polarity, making it reasonably soluble in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The ability of the amine group to engage in hydrogen bonding with water molecules enhances solubility. Solubility is expected to increase in solvents that can donate or accept hydrogen bonds.
  • pH Dependence: The solubility may be affected by the pH of the solution. As an amine, it can become protonated in acidic conditions, potentially increasing its solubility.
  • Solvent Polarity: Non-polar solvents may show limited interaction with the compound, resulting in reduced solubility in such environments.

In conclusion, while 1-(5-fluoro-1H-indol-3-yl)propan-2-amine is likely to be soluble in polar solvents, its solubility profile can exhibit significant dependence on environmental factors such as pH and the nature of the solvent. Its unique combination of functional groups offers interesting avenues to explore in solvent interaction studies.

Interesting facts

Interesting Facts about 1-(5-Fluoro-1H-indol-3-yl)propan-2-amine

1-(5-Fluoro-1H-indol-3-yl)propan-2-amine, often referred to as a substituted indole compound, has garnered attention in the field of medicinal chemistry and pharmacology due to its unique properties and potential applications. Here are some key points that highlight its significance:

  • Mechanism of Action: This compound interacts with various neurotransmitter systems, including serotonin receptors, which might suggest its involvement in modulating mood and anxiety levels.
  • Fluorine Influence: The presence of the fluorine atom in its structure can enhance the compound's bioactivity and bioavailability. Fluorine is known to influence molecular interactions in biological systems.
  • Indole Derivatives: Compounds in the indole family are often noted for their *diverse biological activities*, including anti-cancer, anti-inflammatory, and anti-microbial effects. This makes them a focal point for drug discovery.
  • Research Applications: Scientifically, this compound is utilized in various studies aiming to better understand **receptor binding** and **signal transduction pathways**, particularly in neuropharmacology.
  • Potential Side Effects: As with many pharmacologically active compounds, the structure can also suggest possible side effects which need to be thoroughly investigated in clinical settings to ensure safety.

The synthesis of 1-(5-fluoro-1H-indol-3-yl)propan-2-amine represents an important area in organic chemistry, where the ability to manipulate chemical structures correlates with advancements in drug design. As one researcher noted, "The journey from discovery to application in medicinal chemistry is fraught with challenges, but compounds like this serve as beacons of hope."

Through continued exploration and research, this compound could very well contribute to innovative therapeutic strategies in the future.

Synonyms
5-Fluoro-alpha-methyltryptamine
712-08-3
1-(5-fluoro-1H-indol-3-yl)propan-2-amine
BRN 0475945
5-FLUORO-AMT
3-(2-Aminopropyl)-5-fluoroindole
P46235ZAP7
INDOLE, 3-(2-AMINOPROPYL)-5-FLUORO-
DTXSID70991512
DTXCID101418594
898-722-1
CHEMBL96816
Oprea1_576119
1H-Indole-3-ethanamine, 5-fluoro-.alpha.-methyl-
UNII-P46235ZAP7
SCHEMBL5555870
CTGFDWBZMCPVED-UHFFFAOYSA-N
BDBM50025197
CCG-15903
AKOS005207132
FF79908
PD133502
DB-337289
EN300-359758
2-(5-Fluoro-1H-indol-3-yl)-1-methyl-ethylamine
Q4639589
Z1198156503