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5-MeO-DMT

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Identification
Molecular formula
C13H18N2O
CAS number
1019-45-0
IUPAC name
1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine
State
State

At room temperature, 5-MeO-DMT exists as a solid. The substance is typically handled as either a powder or crystalline solid for various scientific and research applications.

Melting point (Celsius)
69.50
Melting point (Kelvin)
342.65
Boiling point (Celsius)
313.70
Boiling point (Kelvin)
586.85
General information
Molecular weight
218.30g/mol
Molar mass
218.3070g/mol
Density
1.0790g/cm3
Appearence

5-MeO-DMT typically appears as a crystalline powder when synthesized, potentially ranging from white to off-white in color. It can also be found in other forms, such as freebase or as a fumarate salt, oftentimes leading to slight variations in appearance.

Comment on solubility

Solubility of 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine

The solubility of 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine is influenced by a variety of factors, largely due to the presence of functional groups within its structure. Here are some key points to consider:

  • Polarity of the Molecule: The molecule exhibits a significant degree of polarity due to the methoxy group and the amine tails, which often enhances solubility in polar solvents such as water.
  • Solubility in Organic Solvents: It may demonstrate good solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO), owing to the hydrophobic indole ring that can interact favorably with non-polar environments.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature, allowing for greater dissolution in various solvents.
  • pH Sensitivity: The amine group's basicity can lead to ionization in more acidic environments, which might further influence solubility dynamics in aqueous solutions.

In summary, the solubility profile of 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine is multifaceted, revealing critical insights into its potential behavior in various chemical environments. As with many organic compounds, ***the context of the solvent and conditions plays a pivotal role in determining its solubility.***

Interesting facts

Interesting Facts about 1-(5-Methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine

The compound 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-methanamine, often simply referred to as a variant of indole, possesses a fascinating array of properties and applications that intrigue chemists and researchers alike.

Key Features

  • Indole Derivative: As a derivative of indole, this compound is of particular interest due to the biological significance of indole structures, which are present in various natural products and pharmaceutical agents.
  • Potential Biological Activity: Compounds related to indole are often explored for their potential psychoactive properties and therapeutic effects, particularly in the fields of neurology and psychiatry.
  • Research Applications: This compound may serve as a tool in the study of serotonin receptors, given its structural similarity to serotonin itself, thereby offering avenues for understanding mood disorders and other psychological conditions.
  • Natural Product Synthesis: The presence of the methoxy group in this compound indicates potential pathways for synthetic and natural product chemistry, possibly leading to the development of novel organic materials.

Scientific Importance

As scientists delve deeper into the mechanisms of action of such compounds, studies have suggested that small modifications in indole structures can lead to significant changes in biological activity. For example, “The diversity of biologically active compounds derived from indoles is immense, showcasing the versatility of these structures in medicinal chemistry,” a sentiment echoed by many researchers in the field.

This compound not only highlights the intricate relationship between chemical structure and biological function but also embodies the innovation that arises from the field of organic synthesis. Its study could lead to breakthroughs in drug discovery, making it a crucial compound for ongoing research.


Synonyms
5-Methoxygramine
16620-52-3
Methoxygramine
1-(5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine
1H-Indole-3-methanamine, 5-methoxy-N,N-dimethyl-
J6ZN008RY8
INDOLE, 3-((DIMETHYLAMINO)METHYL)-5-METHOXY-
NSC-88885
DTXSID30168081
Indole, 3-[(dimethylamino)methyl]-5-methoxy-
5-METHOXY-N,N-DIMETHYL-1H-INDOLE-3-METHANAMINE
DTXCID2090572
240-669-8
3-Dimethylaminomethyl-5-methoxyindole
MFCD00005630
[(5-methoxy-1H-indol-3-yl)methyl]dimethylamine
N-[(5-Methoxy-1H-indol-3-yl)methyl]-N,N-dimethylamine
1-(5-Methoxy-1h-Indol-3-Yl)-N,N-Dimethyl-Methanamine
3-((Dimethylamino)methyl)-5-methoxyindole
3-[(Dimethylamino)methyl]-5-methoxyindole
5-Methoxy-3-((dimethylamino)methyl)indole
5-Methoxy-3-[(dimethylamino)methyl]indole
[(5-methoxyindol-3-yl)methyl]dimethylamine
EINECS 240-669-8
NSC 88885
2-Dimethylaminomethyl-5-methoxyindole
3-(Dimethylaminomethyl)-5-methoxyindole
5-Methoxy-3-(dimethylaminomethyl)indole
BRN 0170533
5-methoxy gramine
7ZC
5-Methoxygramine, 99%
UNII-J6ZN008RY8
Oprea1_614357
5-22-12-00008 (Beilstein Handbook Reference)
SCHEMBL1196012
CHEMBL3769622
HMS1661A01
NSC88885
SBB003509
STL220640
AKOS005202959
CCG-235466
FM52436
SDCCGMLS-0065813.P001
WLN: T56 BMJ D1N1&1 GO1
AS-76881
SY064526
DB-043644
CS-0214833
ST45244470
E83698
EN300-197563
3-[(Dimethylamino)methyl]-5-methoxy-1H-indole
1-(5-Methoxy-3-indolyl)-N,N-dimethylmethanamine
SR-01000003310
SR-01000003310-1
(5-Methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine #
(5-Methoxy-1H-indol-3-ylmethyl)dimethylamine;1-(5-Methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine