Skip to main content

5-Methoxy-N,N-dimethyltryptamine

ADVERTISEMENT
Identification
Molecular formula
C13H18N2O
CAS number
55-57-8
IUPAC name
1-[5-methoxy-2-methyl-1-(o-tolyl)indol-3-yl]-N,N-dimethyl-methanamine
State
State

At room temperature, 5-Methoxy-N,N-dimethyltryptamine typically exists as a solid. It is sensitive to environmental conditions and may degrade if exposed to heat, moisture, or light over prolonged periods.

Melting point (Celsius)
69.50
Melting point (Kelvin)
342.70
Boiling point (Celsius)
132.50
Boiling point (Kelvin)
405.70
General information
Molecular weight
218.32g/mol
Molar mass
218.3180g/mol
Density
1.1735g/cm3
Appearence

The compound typically appears as a crystalline solid when isolated. It may also be encountered in other forms depending on its preparation and use in various research contexts. The color of the compound can range from off-white to a pale yellowish-white. It is often found in powdered form when prepared for laboratory use.

Comment on solubility

Solubility of 1-[5-methoxy-2-methyl-1-(o-tolyl)indol-3-yl]-N,N-dimethyl-methanamine

The solubility of 1-[5-methoxy-2-methyl-1-(o-tolyl)indol-3-yl]-N,N-dimethyl-methanamine can be influenced by various factors, including its molecular structure and the presence of functional groups.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar regions may favor solubility in non-polar solvents.
  • Temperature: Increased temperature typically promotes greater solubility for many organic compounds.
  • pH: For amines such as the one in this compound, solubility can vary significantly with changes in pH due to protonation.

Generally, compounds with indole structures can exhibit varied solubility profiles; they may be soluble in a variety of organic solvents, yet their solubility in water could be limited due to the complex hydrophobic regions present. Specific data on solubility might be scarce due to the compound's intricate nature, leading to a necessity for empirical testing to determine exact values.

In conclusion, understanding the solubility of this compound requires consideration of its chemical environment and the nature of interactions with different solvents. As with many indole derivatives, the solubility characteristics can be quite nuanced.

Interesting facts

Interesting Facts about 1-[5-Methoxy-2-methyl-1-(o-tolyl)indol-3-yl]-N,N-dimethyl-methanamine

This compound, a fascinating member of the indole family, has garnered attention for several intriguing reasons:

  • Structural Complexity: The presence of both an indole structure and a methoxy group in its formula contributes to its unique properties and potential activities. Indole derivatives are known for their diverse biological roles.
  • Pharmaceutical Potential: Compounds like this one are often explored in medicinal chemistry for their potential pharmacological effects. Their intricate structures can lead to new avenues in drug discovery and development.
  • Research Applications: This compound may play a role in various research studies focused on neurotransmission, as many indole derivatives are known to interact with serotonin receptors, potentially influencing mood and behavior.
  • Biological Activity: The modification with a dimethyl-methanamine group may enhance its binding affinity or bioavailability compared to simpler indole compounds, making it a candidate for further biological evaluation.
  • Versatile Chemistry: Due to its complex nature, this compound offers a canvas for synthetic chemists. It can be used as a starting material for the development of other biologically active molecules.

As a student of chemistry, one might find the study of such compounds especially rewarding. The exploration of structure-activity relationships in indole derivatives often leads to significant breakthroughs in chemistry and medicine. Remember, as Albert Einstein famously stated, "The important thing is not to stop questioning. Curiosity has its own reason for existing."


Thus, delving into compounds like 1-[5-methoxy-2-methyl-1-(o-tolyl)indol-3-yl]-N,N-dimethyl-methanamine signifies not just a study of chemistry but an adventure into the understanding of life's molecular foundations.