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5-Methoxy-2-acetylbenzofuran

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Identification
Molecular formula
C11H10O3
CAS number
61757-63-9
IUPAC name
1-(5-methoxybenzofuran-2-yl)ethanone
State
State

At room temperature, 5-Methoxy-2-acetylbenzofuran is typically in a solid state.

Melting point (Celsius)
63.00
Melting point (Kelvin)
336.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
190.20g/mol
Molar mass
190.1950g/mol
Density
1.2530g/cm3
Appearence

5-Methoxy-2-acetylbenzofuran appears as a light brown solid. It often forms a crystalline powder and can exhibit a faint aromatic odor.

Comment on solubility

Solubility of 1-(5-methoxybenzofuran-2-yl)ethanone

The solubility of 1-(5-methoxybenzofuran-2-yl)ethanone is influenced by several factors, primarily its molecular structure, polarity, and temperature. Here are some key points to consider:

  • Polarity: The methoxy group (-OCH3) attached to the benzofuran structure increases the polarity of the compound, which can enhance its solubility in polar solvents like water.
  • Solvent Types: This compound may exhibit higher solubility in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO) due to the non-polar aromatic structure.
  • Temperature Effects: Generally, increasing the temperature can increase solubility for many organic compounds, which suggests that heating solutions containing this compound may improve dissolution rates.

Overall, while 1-(5-methoxybenzofuran-2-yl)ethanone is likely to be more soluble in organic solvents, its specific solubility characteristics can vary significantly under different environmental conditions. When exploring the uses of this compound, it is essential to test solubility in the intended solvent systems to ensure effective application.

Interesting facts

Interesting Facts about 1-(5-Methoxybenzofuran-2-yl)ethanone

1-(5-Methoxybenzofuran-2-yl)ethanone is a fascinating compound that finds its roots in both organic chemistry and medicinal applications. It features a unique structure that combines a benzofuran moiety with an ethanone group, creating a compound with interesting properties. Here are some noteworthy aspects:

  • Structural Significance: The presence of the methoxy group enhances the electron density of the benzofuran ring, influencing its chemical reactivity and potential interaction with biological systems.
  • Psychoactive Potential: Compounds related to benzofurans have garnered attention in the field of psychoactive substances, with research exploring their effects on the central nervous system. Some may have implications for therapeutic applications.
  • Natural Occurrences: Benzofuran derivatives are often found in various plants and may play significant roles as secondary metabolites, contributing to the plant's protective mechanisms or attractive scents.
  • Medical Research: Ongoing studies have considered the role of similar compounds in developing new pharmaceuticals, particularly in treating neurological disorders, highlighting the continual relevance of such compounds in drug discovery.
  • Reactivity Profile: The reactivity of 1-(5-methoxybenzofuran-2-yl)ethanone can be investigated further through various synthetic pathways, allowing chemists to explore the formation of novel derivatives and their potential applications.

In summary, 1-(5-methoxybenzofuran-2-yl)ethanone embodies the elegance of organic chemistry while suggesting a breadth of biological and therapeutic possibilities. As research progresses, compounds like this are likely to unlock new avenues in both understanding nature's chemistry and developing innovative treatments.

Synonyms
Ethanone, 1-(5-methoxy-2-benzofuranyl)-
1-(5-Methoxy-2-benzofuranyl)ethanone
BRN 1284242
5-Methoxy-2-benzofuranyl methyl ketone
DTXSID00175949
KETONE, 5-METHOXY-2-BENZOFURANYL METHYL
5-18-01-00454 (Beilstein Handbook Reference)
RefChem:341259
DTXCID3098440
Ethanone, 1-(5-methoxy-2-benzofuranyl)-(9CI)
21587-39-3
2-ACETYL-5-METHOXYBENZOFURAN
1-(5-methoxy-1-benzofuran-2-yl)ethanone
1-(5-Methoxybenzofuran-2-yl)ethan-1-one
2-acetyl-5-methoxybenzo[b]furan
MFCD01716424
1-(5-methoxy-2-benzofuranyl)-Ethanone
SCHEMBL1287553
1-(5-methoxybenzofuran-2-yl)ethanone
AKOS002678534
AS-40654
DB-066565
CS-0029601
Ethanone, 1-(5-methoxy-2-benzofuranyl)- (9CI)
A1-18437