Skip to main content

Nitrofurazone

ADVERTISEMENT
Identification
Molecular formula
C6H6N4O3S
CAS number
59-87-0
IUPAC name
1-[(5-nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol
State
State

Nitrofurazone is generally a solid at room temperature.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
362.88
Boiling point (Kelvin)
636.03
General information
Molecular weight
198.16g/mol
Molar mass
198.1570g/mol
Density
1.7100g/cm3
Appearence

Nitrofurazone typically presents as a yellow, crystalline solid. It may come in fine powder form or as small granules, which are sensitive to light. This compound might emit a slight odor, reminiscent of rubber.

Comment on solubility

Solubility of 1-[(5-nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol

Understanding the solubility of a compound like 1-[(5-nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol is essential for its applications in various chemical processes. The solubility of this compound can be influenced by several factors:

  • Polarity: Being a thiol, it has polar characteristics due to the presence of the -SH group which often enhances solubility in polar solvents like water.
  • Functional Groups: The presence of nitro and heteroatoms in its structure can significantly impact solubility when interacting with solvent molecules.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can also contribute to its solubility in certain solvents, potentially increasing its overall solubility.
  • pH Dependence: The solubility may vary with changes in pH, as protonation or deprotonation of functional groups can alter interactions with the solvent.

In practical terms, it is often observed that thiol compounds such as this one tend to be more soluble in organic solvents and can be less soluble in water, especially if they have substantial hydrophobic characteristics. Thus, it is important to consider both chemical structure and environmental conditions for understanding their solubility profile.

As a final note, when working with this compound, conducting empirical solubility tests in various solvents can provide valuable insights and lead to better applications in pharmaceutical or agricultural chemistry.

Interesting facts

Exploring 1-[(5-Nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol

1-[(5-Nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol is an intriguing compound that has garnered attention in the fields of medicinal chemistry and agrochemistry. Here are some compelling facts about this compound:

  • Versatile Applications: This compound exhibits potential therapeutic properties, making it a candidate for drug development. Its structure hints at opportunities for modification to enhance biological activity.
  • Furyl Moiety: The presence of a nitro-substituted furan ring is significant. Furans are known for their diverse range of biological activities, including anti-inflammatory and anti-cancer effects.
  • Thiol Group: The thiol functional group is critical. It has notable implications in redox reactions and can serve as a nucleophile in various chemical reactions.
  • Bioactivity: Research has indicated that compounds containing the imidazole ring often display activities against various pathogens, including bacteria and fungi, suggesting 1-[(5-nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol could have a similar efficacy.
  • Research Interest: Due to its unique structure, this compound has become a subject of study in the search for novel therapeutic agents, particularly in the fight against drug-resistant pathogens.

As with many chemical compounds, the journey of understanding and utilizing 1-[(5-nitro-2-furyl)methyleneamino]-4,5-dihydroimidazole-2-thiol emphasizes the importance of interdisciplinary research and collaboration in the realm of chemical science. Its multifaceted properties continue to inspire investigations into its potential utility in modern medicine.