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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one
State
State

Nitrofurazone is a solid at room temperature and can commonly be found in the form of ointments or as an ingredient in first aid creams.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1570g/mol
Density
1.6630g/cm3
Appearence

Nitrofurazone typically appears as a bright yellow crystalline solid. The compound is sensitive to light and may become brown upon prolonged exposure.

Comment on solubility

Solubility of 1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one

The solubility of 1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one can vary significantly depending on the solvent and conditions. Here are some important points to consider:

  • Polar Solvents: This compound is likely to show moderate solubility in polar solvents such as water and methanol. The presence of polar functional groups can enhance interactions with polar solvent molecules.
  • Non-Polar Solvents: In non-polar solvents like hexane or benzene, solubility may be limited. Compounds with high polarity often do not dissolve well in non-polar environments.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature. Heating the solvent may facilitate better solvation of the compound.
  • pH Sensitivity: The solubility of this compound may be affected by the pH of the solution, especially if it contains ionizable groups. Thus, testing solubility across different pH levels can yield varying results.

In general, solubility is a critical property that influences the behavior of compounds in chemical reactions, biological systems, and environmental contexts. As a result, understanding the solubility profile of 1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one is essential for its application in various fields.

Interesting facts

Interesting Facts about 1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one

1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one is a fascinating compound that bridges the gap between organic chemistry and medicinal applications. This compound features notable structural elements that enhance its reactivity and biological importance.

Chemical Structure and Reactivity

Its unique structure can be broken down into significant constituents:

  • Imidazolidin-2-one: The presence of this five-membered ring provides stability and makes it a noteworthy participant in various chemical reactions.
  • 5-Nitro-2-furyl group: A nitro-substituted furan ring is known for its electron-withdrawing effects, which can influence the compound's reactivity and interaction with biological targets.

Potential Applications

This compound is not just interesting from a structural standpoint; it also exhibits potential applications in various fields:

  • Pharmaceutical Chemistry: Compounds containing furan and imidazolidine derivatives have been studied for their anti-cancer and antimicrobial properties.
  • Material Science: The unique structural attributes can potentially lead to new polymers or materials with desirable properties.

Biological Significance

Its biological implications are particularly noteworthy. As researchers explore new therapeutic agents:

  • This compound can act as a lead structure for developing derivatives with improved efficacy.
  • The interaction of the nitro group with biological macromolecules offers avenues for comprehension of disease mechanisms.

In summary, 1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one represents a rich area of study, where its intriguing structure, potential applications, and biological significance come together to pave the way for further exploration.