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Sarpogrelate hydrochloride

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Identification
Molecular formula
C24H31Cl2N3O2
CAS number
135159-51-2
IUPAC name
1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone;dihydrochloride
State
State

Sarpogrelate hydrochloride is a solid at room temperature.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
397.40
Boiling point (Kelvin)
670.55
General information
Molecular weight
501.44g/mol
Molar mass
501.4400g/mol
Density
1.2700g/cm3
Appearence

Sarpogrelate hydrochloride appears as a white to off-white crystalline powder. It is typically provided in its dihydrochloride form for medicinal uses.

Comment on solubility

Solubility of 1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone; dihydrochloride

The solubility of this compound is notably influenced by its complex structure, which includes both aromatic and heterocyclic components. To better understand its solubility properties, we can consider several factors:

  • Polarity: Due to the presence of a dihydrochloride moiety, the compound likely exhibits increased polarity, which can enhance its solubility in polar solvents like water.
  • Hydrogen bonding: The hydroxyl group in the piperazine structure can form hydrogen bonds with solvents, contributing to solubility.
  • Hydrophobic interactions: The aromatic parts of the molecule may reduce solubility in highly polar solvents but increase solubility in organic solvents.
  • Temperature effect: As with many chemical compounds, solubility may increase with temperature, making it more soluble at elevated temperatures.

In summary, the solubility of this compound can be described as moderate to high in water, depending on environmental conditions. It may exhibit varying solubility in organic solvents, influenced by factors such as pH and the solvent's nature. Understanding these characteristics is crucial for applications in pharmaceuticals and chemical research.

Interesting facts

Interesting Facts about 1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone; dihydrochloride

This compound belongs to a fascinating class of molecules known as benzazepins, which are known for their diverse range of biological activities. Here are some intricate details that showcase the importance of this compound in scientific research:

  • Pharmacological Potential: Benzazepins are often studied for their potential use in treating various neurological and psychiatric disorders. Research into related compounds suggests this one may also exhibit similar therapeutic properties.
  • Structural Diversity: The unique structure of this compound, featuring both piperazine and hydroxyethyl functional groups, can lead to varied interactions with biological targets, making it a candidate for new drug development.
  • Research Applications: Ongoing studies are exploring the mechanism of action of similar compounds, which can help elucidate their effects at the molecular level. This might lead to improved understanding of how they modulate neurotransmitter systems.
  • In Silico Modeling: The compound's complex molecular structure makes it an interesting subject for computational chemistry studies, which can help predict how this molecule will interact with different targets in the body.
  • Synergistic Effects: When combined with other pharmacologically active compounds, benzazepins might exhibit synergistic effects, potentially enhancing their efficacy or reducing side effects, a topic of active research.

As we continue to explore such compounds, the hope is to unlock new therapeutic pathways that can lead to breakthroughs in medicine. The study of 1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone; dihydrochloride exemplifies the rich intersection of chemistry and biology that is pivotal in the development of new pharmaceuticals.

Synonyms
29573-86-2
Ketone, 10,11-dihydro-5H-dibenz(b,f)azepin-5-yl (4-(2-hydroxyethyl)piperazinyl)methyl, dihydrochloride
DTXSID20183748
RefChem:350388
DTXCID60106239