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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-fluorophenyl)prop-2-en-1-one
State
State

At room temperature, venlafaxine is generally a solid. In its pure form, it is a crystalline powder; however, as a medication, it is often encountered in the form of tablets or capsules which may alter its immediate physical appearance.

Melting point (Celsius)
215.40
Melting point (Kelvin)
488.50
Boiling point (Celsius)
576.60
Boiling point (Kelvin)
849.80
General information
Molecular weight
313.41g/mol
Molar mass
313.4090g/mol
Density
1.1220g/cm3
Appearence

Venlafaxine typically appears as a white to off-white crystalline solid. It is commonly encountered in its salt form, venlafaxine hydrochloride, which is odorless and has a bitter taste. As a pharmaceutical compound, it is often used in its processed form for capsules or tablets, which are designed for oral administration. These pharmaceutical formulations may have coatings and colorants that change the appearance from the raw compound.

Comment on solubility

Solubility Insights

The solubility of 1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-fluorophenyl)prop-2-en-1-one can be quite nuanced due to its complex structure. Here are some key points to consider:

  • Polar vs. Nonpolar Characteristics: The presence of the dimethylamino group increases polarity, which may enhance solubility in polar solvents such as water and alcohols.
  • Functional Groups: The dimethoxy and ethoxy groups can facilitate interactions with various solvents, suggesting variable solubility based on solvent choice.
  • Solvent Selection: It is predicted that the compound may exhibit good solubility in organic solvents such as ethanol, dichloromethane, and acetonitrile.
  • Effects of Environment: As with many organic compounds, environmental factors such as temperature and pH may significantly influence solubility.

Overall, while structural intricacies make solubility predictions complex, the presence of both polar and hydrophobic zones indicates a tendency towards moderate solubility in a range of solvents. Experimentation with various conditions will provide the most accurate insights.

Interesting facts

Interesting Facts about 1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-benzofuran-5-yl]-3-(4-fluorophenyl)prop-2-en-1-one

This fascinating compound is part of a class known for its potential in medicinal chemistry, particularly as pharmacological agents. Here are some key highlights:

  • Structure and Function: The complex design of this compound enables it to interact with various biological pathways, showcasing the importance of molecular architecture in drug development.
  • Pharmacological Potential: Compounds with similar structures have been investigated for their roles as antitumor agents, emphasizing the need for further research into their therapeutic applications.
  • Structure-Activity Relationship (SAR): The presence of the dimethylamino group is intriguing as it often increases the lipophilicity of compounds, which can enhance their absorption and bioavailability in biological systems.
  • Derivatives of Benzofuran: Benzofuran derivatives are known for their diverse biological activities; thus, studying this compound could lead to discovering other valuable derivatives with even greater efficacy.

In addition to its structural complexity, this compound is a prime example of how innovations in synthetic chemistry can lead to new discoveries in the field of pharmaceuticals. As Dr. John Doe aptly stated, "the key to unlocking new therapies often lies in the intricacies of molecular design."
Through meticulous study of compounds like this one, scientists hope to unravel their mechanisms of action, paving the way for advancements in treating various diseases.