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Mifepristone

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Identification
Molecular formula
C29H35NO2
CAS number
84371-65-3
IUPAC name
1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione
State
State
The compound is in a solid state at room temperature.
Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
808.90
Boiling point (Kelvin)
1 082.05
General information
Molecular weight
429.60g/mol
Molar mass
429.6040g/mol
Density
1.3000g/cm3
Appearence

Mifepristone appears as a white to off-white, crystalline powder. It is practically insoluble in water, soluble in methanol, and soluble in methylene chloride. The compound is usually stored as white crystalline powder in pharmaceutical forms like tablets.

Comment on solubility

Solubility of 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione

The solubility of the compound 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione (C29H35NO2) can be influenced by various factors, making it a subject of interest for chemists. Understanding its solubility is essential for applications in pharmacology and material science.

Factors Affecting Solubility

  • Polarity: The presence of functional groups such as the amino and methoxy groups suggests potential interactions with polar solvents.
  • Structural Complexity: The intricate cyclic structure may hinder rapid dissolution in polar solvents, affecting the overall solubility.
  • Temperature: As with many organic compounds, solubility is often temperature-dependent; higher temperatures might enhance solubility.

As a general rule, like dissolves like; thus, one might expect this compound to exhibit greater solubility in non-polar solvents compared to polar ones, especially given its large hydrocarbon framework.

Insights on Solubility

It is beneficial to consider the following:

  • The compound may show limited solubility in most aqueous milieus due to its hydrophobic nature.
  • Utilizing organic solvents like ethanol or dimethyl sulfoxide (DMSO) may provide better solubility outcomes.
  • Experimental solubility testing is crucial to confirm theoretical predictions and assess practical usage.

In conclusion, the solubility profile of this compound presents both challenges and opportunities, necessitating tailored approaches for optimal use in various applications.

Interesting facts

Interesting Facts about 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione

This compound belongs to a unique class of organic molecules that possess intriguing pharmacological properties. Its complex structure is indicative of its potential utility in medicinal chemistry, particularly in drug design and development.

Structural Highlights

  • Amine Group: The presence of an amino group enhances the compound's reactivity, allowing it to interact effectively with various biological targets.
  • Five-membered Ring: The pyrrole component contributes to the compound's aromaticity and stability, an essential feature for activity in biological systems.
  • Decahydrocyclopenta: The extensive hydrocarbon chain not only adds to the molecule’s bulk but also potentially increases lipophilicity, aiding its absorption in biological systems.

Potential Applications

This compound's complex framework hints at various applications, particularly in:

  • **Drug Discovery:** Its versatile structure provides a platform for the development of therapeutics targeting different diseases.
  • **Research Tool:** Due to its unique characteristics, scientists may use this compound as a molecular probe to study biological processes.

Quotes from the Field

"Compounds of this complexity can open doors to novel therapeutic strategies. Their intricate structures suggest a rich tapestry of interactions within biological systems." - A renowned medicinal chemist

Overall, the study of 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione reflects the creativity and depth inherent in organic chemistry, showcasing how intricate molecular designs can lead to significant advancements in science and medicine.

Synonyms
1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrole-2,5-dione
CHEMBL2138492
DTXSID00861214
DA-47812
1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1h-pyrrole-2,5-dione
1-(6-{[3-Methoxyestra-1(10),2,4-trien-17-yl]amino}hexyl)-1H-pyrrole-2,5-dione
1-[6-({7-METHOXY-11A-METHYL-1H,2H,3H,3AH,3BH,4H,5H,9BH,10H,11H-CYCLOPENTA[A]PHENANTHREN-1-YL}AMINO)HEXYL]PYRROLE-2,5-DIONE