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1-(6-Chloro-1H-indol-3-yl)butan-2-amine

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Identification
Molecular formula
C12H15ClN2
CAS number
166329-55-3
IUPAC name
1-(6-chloro-1H-indol-3-yl)butan-2-amine
State
State

The compound exists as a solid at room temperature, typically forming a crystalline structure.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.00
General information
Molecular weight
222.72g/mol
Molar mass
222.6950g/mol
Density
1.2510g/cm3
Appearence

The compound typically appears as a crystalline solid. Its coloration can vary, but it is often found in forms that are off-white to light tan depending on purity and specific crystalline structure.

Comment on solubility

Solubility Insights for 1-(6-chloro-1H-indol-3-yl)butan-2-amine

The solubility of the compound 1-(6-chloro-1H-indol-3-yl)butan-2-amine is a crucial factor that influences its behavior in biological systems and chemical reactions. Understanding its solubility can help predict its applications and effectiveness in various conditions. Here are some key points to consider:

  • Polarity: This compound features both hydrophobic and hydrophilic regions due to its indole structure and amine group, which suggests that it may exhibit partial solubility in polar solvents like water.
  • Solvent Interaction: It is likely to be more soluble in organic solvents such as DMSO or ethanol, given the presence of the chloro-substituted indole.
  • Temperature Dependence: As with many organic compounds, its solubility may increase with temperature. Conducting solubility tests at various temperatures can provide valuable insight.
  • pH Sensitivity: The amine group may lead to varying solubility at different pH levels. For example, it could become protonated in acidic conditions, enhancing its solubility in aqueous environments.

In summary, the solubility of 1-(6-chloro-1H-indol-3-yl)butan-2-amine can vary significantly based on several factors, including solvent choice, temperature, and pH. Laboratory assessments are essential for precisely determining its solubility characteristics, which can ultimately dictate its usability in pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about 1-(6-chloro-1H-indol-3-yl)butan-2-amine

1-(6-chloro-1H-indol-3-yl)butan-2-amine is a fascinating compound that showcases the intricate world of organic chemistry. Here are some intriguing aspects:

  • Structural Diversity: The compound comprises an indole structure, which is a foundational framework in many biologically active compounds. This indole moiety plays a critical role in the chemical reactivity and biological activity of the molecule.
  • Chlorination Impact: The presence of the chlorine atom at the 6-position of the indole ring often modifies the compound's properties, potentially enhancing its reactivity and interaction with biological targets.
  • Biological Relevance: Compounds derived from indoles, like this one, are extensively studied in pharmacology for their potential as therapeutic agents. They have been linked to numerous biological activities, including anticancer, antimicrobial, and anti-inflammatory effects.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step organic reactions, showcasing the complexity and creativity inherent in organic synthesis. Understanding these pathways is essential for chemists who wish to design and develop new compounds.
  • Research Potential: Given its unique structure, this compound is of interest in research fields focused on medicinal chemistry and drug development. Its potential mechanisms of action can open doors to new therapeutic strategies.

In conclusion, 1-(6-chloro-1H-indol-3-yl)butan-2-amine exemplifies the intersection of structural complexity and biological importance, making it a key subject of study in contemporary chemical research.

Synonyms
AKOS020811557