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Sumatriptan

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Identification
Molecular formula
C14H21ClN2}OS
CAS number
103628-46-2
IUPAC name
1-[(6-chloro-1H-indol-3-yl)methyl]propylammonium;chloride
State
State

Sumatriptan is commonly in the solid state at room temperature, as either a powder or crystalline solid.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
280.40
Boiling point (Kelvin)
553.55
General information
Molecular weight
413.92g/mol
Molar mass
413.9160g/mol
Density
1.3000g/cm3
Appearence

Sumatriptan appears as a white to off-white powder. Its solid form is typically crystalline.

Comment on solubility

Solubility of 1-[(6-chloro-1H-indol-3-yl)methyl]propylammonium;chloride

The solubility of 1-[(6-chloro-1H-indol-3-yl)methyl]propylammonium;chloride (or its nature as a salt) can be intriguing, influenced by both its ionic structure and polar characteristics.

Key points regarding solubility:

  • This compound is likely to be soluble in water because it contains a quaternary ammonium ion, which typically enhances water solubility due to its ionic nature.
  • Its solubility might also be affected by the presence of the 6-chloro-1H-indole moiety, potentially introducing some hydrophobic characteristics.
  • In organic solvents such as ethanol or methanol, the solubility might vary and can be less than in water due to differing interactions.

As with many compounds where the balance between hydrophilic and hydrophobic regions exists, one might note that “like dissolves like” tends to apply. Thus, testing solubility in various solvents can provide fascinating insights into this compound’s behavior. Additionally, factors such as temperature and pH may also play vital roles in its solubility profile.

Interesting facts

Interesting Facts about 1-[(6-chloro-1H-indol-3-yl)methyl]propylammonium;chloride

This compound, known for its intriguing structure, holds a notable presence in the field of medicinal chemistry and pharmacology. Here are some fascinating insights:

  • Structural Uniqueness: The molecule features a chloro-substituted indole core, which is recognized for its ability to exhibit diverse biological activities including antitumor and antiviral properties.
  • Chiral Center: Present within the structure is a chiral center, influencing the compound's interaction with biological systems. This chiral aspect is crucial in drug discovery, as it can affect the efficacy and safety of potential therapeutic agents.
  • Potential Applications: Researchers are exploring its potential roles in:
    • Neurological disorders
    • Anti-inflammatory responses
    • Antidepressant properties
  • Combating Resistance: Compounds like this are essential in developing new strategies to combat drug-resistant pathogens, paving the way for innovative treatments.
  • Quaternary Ammonium Salt: As a chloride salt, the ammonium moiety plays a critical role in enhancing the compound's solubility and bioavailability, which are key considerations in drug formulation.

In summary, 1-[(6-chloro-1H-indol-3-yl)methyl]propylammonium;chloride is more than just a chemical formula; it represents a blend of chemistry and potential that could reshape therapeutic approaches. As research continues, this compound may unlock new pathways in treatment modalities, making it an exciting subject of study in the chemical sciences.

Synonyms
3-(2-Aminobutyl)-6-chloroindole hydrochloride
1446-77-1
INDOLE, 3-(2-AMINOBUTYL)-6-CHLORO-, HYDROCHLORIDE