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Fenobucarb

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Identification
Molecular formula
C15H14N2O2S
CAS number
3767-28-0
IUPAC name
1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea
State
State

At room temperature, Fenobucarb is typically a solid. Its crystalline form allows it to be easily handled in this state for various applications.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
412.20
Boiling point (Kelvin)
685.35
General information
Molecular weight
225.28g/mol
Molar mass
225.2760g/mol
Density
1.3400g/cm3
Appearence

Fenobucarb appears as a brown or white crystalline solid. It is often characterized by a distinct chemical smell that is typical of carbamates. The specific appearance can vary slightly depending on the specific impurities and the processing methods used.

Comment on solubility

Solubility of 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea

The solubility of 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea can be influenced by various factors including its molecular structure and the nature of the solvent used. Here are some key points regarding its solubility:

  • Polarity: The compound features both non-polar (phenyl) and polar (urea and benzothiazole) regions, which suggests a potential for moderate solubility in polar solvents such as water, while possibly exhibiting better solubility in organic solvents.
  • Temperature: Like many compounds, solubility may increase with rising temperature, facilitating its dissolution in specific solvents.
  • Interactions: The presence of functional groups, such as urea and methoxy, can engage in hydrogen bonding, enhancing solubility in polar solvents.

As emphasized by the observation that “like dissolves like,” the solubility of this compound may be greater in solvents that share similar polar characteristics. Understanding its solubility profile is crucial for various applications, particularly in medicinal chemistry where solubility can influence bioavailability and efficacy.

Interesting facts

Interesting Facts about 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea

1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea is an intriguing compound with a variety of applications and properties that make it a subject of interest among chemists and pharmacologists alike. Here are some key points about this fascinating molecule:

  • Structure and Design: This compound features a unique combination of a urea moiety and a benzothiazole ring, which contributes to its biological activity. The design allows for multiple interactions within biological systems, making it an excellent candidate for drug development.
  • Biological Activity: Compounds like this one often exhibit promising pharmacological properties. Research indicates that benzothiazole derivatives may possess antitumor, antibacterial, and anti-inflammatory effects, suggesting potential roles in therapeutic applications.
  • Mechanism of Action: The presence of the methoxy group can enhance the lipophilicity and stability of the compound, which is crucial for its interaction with target sites in biological systems. This modification can influence the pharmacodynamics significantly.
  • Versatile Applications: Due to its biological properties, this compound could be explored in various fields including medicinal chemistry, agriculture (as a plant growth regulator), and material sciences for developing advanced materials.
  • Research Potential: The ongoing exploration of similar derivatives continues to reveal new pathways for synthesis and application. This compound could serve as a lead structure for synthesizing new, more effective therapeutic agents.

In summary, 1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea stands as a testament to the creativity and innovation in chemistry. As the field evolves, it will be exciting to uncover new uses and understand the mechanisms driving its biological activities.

Synonyms
FRENTIZOLE
26130-02-9
Frentizol
Frentizolum
Compound 53616
1-(6-Methoxy-2-benzothiazolyl)-3-phenylurea
DTXSID5046279
7EY946394I
COMPOUND-53616
DTXCID3026279
RefChem:600392
666-432-2
Urea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-
1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylurea
MLS000555007
CHEMBL128988
1-(6-methoxybenzothiazol-2-yl)-3-phenylurea
1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea
3-(6-methoxy-1,3-benzothiazol-2-yl)-1-phenylurea
NCGC00160657-01
SMR000147124
1-(6-Methoxy-benzothiazol-2-yl)-3-phenyl-urea
CAS-26130-02-9
Frentizol [INN-Spanish]
Frentizolum [INN-Latin]
LY 53616
Frentizole [USAN:INN:BAN]
UNII-7EY946394I
FRENTIZOLE [INN]
Frentizole (USAN/INN)
Opera_ID_1653
FRENTIZOLE [USAN]
FRENTIZOLE [WHO-DD]
Oprea1_516941
cid_33334
MLS001201824
SCHEMBL599582
orb1299738
SCHEMBL18313924
HMS2233G12
HMS3370C02
BBA13002
Tox21_111964
BDBM50189352
MFCD00030234
s2418
STK078558
AKOS001049350
Tox21_111964_1
CS-0841
NCGC00160657-03
BS-42180
DA-63613
HY-15374
NS00122519
ST50103599
D00159
F21331
EN300-1700017
1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenyl-urea
BRD-K07202345-001-15-2
BRD-K07202345-001-19-4
N-(6-methoxy-1,3-benzothiazol-2-yl)-N'-phenylurea
Q27268177
Z44584301
N-(6-methoxybenzothiazol-2-yl)(phenylamino)carboxamide
1-(6-METHOXY-3H-BENZOTHIAZOL-2-YLIDENE)-3-PHENYL-UREA