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Carvedilol

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Identification
Molecular formula
C24H26N2O4
CAS number
72956-09-3
IUPAC name
1-[7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran-2-yl]ethanone
State
State

Carvedilol is typically in a solid state at room temperature.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
486.10
Boiling point (Kelvin)
759.30
General information
Molecular weight
406.49g/mol
Molar mass
406.4890g/mol
Density
1.2000g/cm3
Appearence

Carvedilol appears as a white to almost white crystalline powder.

Comment on solubility

Solubility of 1-[7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran-2-yl]ethanone (C24H26N2O4)

The solubility of 1-[7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran-2-yl]ethanone, a complex organic compound, can be influenced by various factors such as its molecular structure, functional groups, and the nature of the solvent. Generally, here are some key points regarding its solubility:

  • Hydrophilicity vs. Hydrophobicity: The presence of functional groups, like the hydroxyl (-OH) and amino (-NH) groups, suggests that this compound may exhibit some degree of hydrophilicity, which can enhance its solubility in polar solvents like water.
  • Solvent Compatibility: It is probable that this compound is more soluble in organic solvents such as ethanol, methanol, or acetone due to its large hydrocarbon structure, which increases its overall hydrophobic character.
  • Temperature Dependence: Solubility is often temperature-dependent, with most solids showing increased solubility at higher temperatures; thus, warmer conditions may facilitate the dissolution of this compound.
  • Concentration Effects: In concentrated solutions, solubility may also be impacted by interactions between solute molecules, leading to saturation limits.

In conclusion, while the specific solubility data for this compound requires empirical measurement, understanding these factors can provide insights into its solubilization behavior. Further research and experimental approaches are essential to determine precise solubility characteristics.

Interesting facts

Interesting Facts about 1-[7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran-2-yl]ethanone

This fascinating compound boasts a unique blend of structural elements that make it noteworthy in the realms of medicinal chemistry and pharmacology. Here are some key points:

  • Structural Features: The compound features a complex benzofuran core, which is a fused ring structure comprising a benzene ring and a furan ring. This structure contributes to its potential biological activity.
  • Biological Significance: Compounds similar in structure to this benzofuran derivative have been studied for their effects on various biological systems, suggesting potential applications in drug development.
  • Amine Group Influence: The presence of the isopropylamino group is noteworthy; amines are often critical in medicinal chemistry because they can affect the solubility and binding properties of the compound, which can enhance its pharmacological effects.
  • Hydroxyl Group Role: The hydroxyl (-OH) functional group not only increases solubility but also can engage in hydrogen bonding, possibly enhancing interactions with biological targets.
  • Potential Applications: Given its structural complexity, researchers may explore this compound's potential in treating specific conditions such as neurological disorders or cancer. The innovative combinations within molecular frameworks like this one can lead to the discovery of novel therapeutic agents.

Furthermore, the study of derivatives of this compound can lead to fascinating insights into structure-activity relationships (SAR), helping scientists understand how small changes in structure can lead to significant changes in activity. As chemists continue to unravel the complexities of such compounds, the possibilities for new advancements in medicine remain limitless.

Synonyms
Befunolol
39552-01-7
Befunolol [INN]
Befunololum
Befunololum [INN-Latin]
Bentos
befunolol hydrochloride
7-(2-Hydroxy-3-(isopropylamino)propoxy)-2-benzofuranyl methyl ketone
Befunolol (INN)
Glauconex
BRN 3620832
UNII-418546MT3A
BEFUNOLOL [MI]
418546MT3A
BFE 60
BEFUNOLOL [WHO-DD]
2-Acetyl-7-(2-hyroxy-3-isopropylaminopropoxy)benzofuran
DTXSID80865957
1-[7-[2-hydroxy-3-(propan-2-ylamino)propoxy]-1-benzofuran-2-yl]ethanone
1-(7-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)ethanone
Ethanone, 1-(7-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)-
(+/-)-Befunolol
( inverted exclamation markA)-Befunolol
2-acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran
Befunololum (INN-Latin)
Bentos (TN)
1-(7-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)ethanone hydrochloride
KETONE, 7-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)-2-BENZOFURANYL METHYL
2-acetyl-7-(2-hydroxy-3-isopropylamino)propoxybenzofuran
1-(7-{2-Hydroxy-3-[(propan-2-yl)amino]propoxy}-1-benzofuran-2-yl)ethan-1-one
befunololo
1-(7-(2-Hydroxy-3-((propan-2-yl)amino)propoxy)-1-benzofuran-2-yl)ethan-1-one
()-Befunolol
1-[7-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]ethanone; (+/-)-Befunolol; 2-Acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran; Befunolol; (+/-)-Befunolol;
(??)-Befunolol
SCHEMBL78720
CHEMBL153984
DTXCID40814305
S01ED06
CHEBI:135212
1-[7-[2-hydroxy-3-[(1-methylethyl)-amino]propoxy]-2-benzofuranyl]ethanone
AKOS040740969
CS-6588
DB09013
NCGC00522022-01
DB-345646
HY-101752
NS00009059
D07496
Q4880388
Ethanone, 1-(7-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)-(9CI)