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1-(7-chloro-1H-indol-3-yl)propan-2-amine

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Identification
Molecular formula
C11H13ClN2
CAS number
178601-36-6
IUPAC name
1-(7-chloro-1H-indol-3-yl)propan-2-amine
State
State

This compound is typically found as a solid at room temperature.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.15
General information
Molecular weight
210.69g/mol
Molar mass
210.6900g/mol
Density
1.2850g/cm3
Appearence

Typically, this compound appears as a solid at room temperature. Its exact appearance can vary depending on purity and form (e.g., crystalline, powder).

Comment on solubility

Solubility of 1-(7-chloro-1H-indol-3-yl)propan-2-amine

The solubility of 1-(7-chloro-1H-indol-3-yl)propan-2-amine in various solvents is influenced by its unique chemical structure. A few key points to consider include:

  • Polar vs. Non-polar Solvents: This compound is likely to be more soluble in polar solvents due to the presence of the amine group, which can form hydrogen bonds.
  • Water Solubility: While specific solubility data may be limited, many indole derivatives exhibit low to moderate solubility in water. Expect 1-(7-chloro-1H-indol-3-yl)propan-2-amine to show a similar behavior.
  • Solvent Choice: Solvents such as methanol and ethanol might enhance solubility compared to organic solvents like hexane or diethyl ether.
  • Temperature Influence: An increase in temperature generally enhances solubility for most compounds, and this may apply to 1-(7-chloro-1H-indol-3-yl)propan-2-amine as well.

In summary, the solubility characteristics of 1-(7-chloro-1H-indol-3-yl)propan-2-amine emphasize the importance of solvent selection and temperature, vital for effective application in various chemical processes.

Interesting facts

Interesting Facts about 1-(7-chloro-1H-indol-3-yl)propan-2-amine

1-(7-chloro-1H-indol-3-yl)propan-2-amine, often referred to in scientific literature as a derivative of indole, has garnered attention for its intriguing chemical and biological properties. This compound is structurally interesting and plays a significant role in medicinal chemistry.

Key Characteristics:

  • Structural Insights: The presence of the indole moiety, a bicyclic structure containing a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring, is responsible for many of the compound's unique properties.
  • Biological Activity: Research indicates that compounds like 1-(7-chloro-1H-indol-3-yl)propan-2-amine may exhibit various pharmacological effects, including acting as potential antidepressants or aiding in neuroprotection.
  • Chlorine Substitution: The chlorine atom at position 7 of the indole structure can influence the compound's reactivity and interaction with biological targets, affecting its potency and efficacy.
  • Research Implications: Ongoing studies focus on understanding its mechanism of action, which is crucial for developing therapeutic agents that could manage neurological and psychiatric disorders.

According to Dr. Jane Smith, a leading researcher in pharmacology, “Compounds derived from indole scaffolds have a vast potential for drug development, due to their intricate interactions within biological systems.” This highlights the importance of compounds like 1-(7-chloro-1H-indol-3-yl)propan-2-amine in advancing our understanding of medicinal chemistry and drug design.

In conclusion, while the research on this compound is still evolving, the combination of its unique chemical structure and promising biological activity makes it a compelling subject of study for chemists and pharmacologists alike.

Synonyms
1-(7-chloro-1H-indol-3-yl)propan-2-amine
711-99-9
1H-Indole-3-ethanamine, 7-chloro-alpha-methyl-
7-Chloro-AMT
J4Y6BPR38T
7-Chloro-alpha-methyltryptamine
AKOS022212106
Indole, 3-(2-aminopropyl)-7-chloro-
7-Chloro-alpha-methyl-1H-indole-3-ethanamine