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Methylenedioxyamphetamine (MDA)

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Identification
Molecular formula
C10H13NO3
CAS number
4764-17-4
IUPAC name
1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine
State
State

MDA is typically a solid at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
96.50
Melting point (Kelvin)
369.65
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2190g/mol
Density
1.1210g/cm3
Appearence

MDA typically appears as a white to off-white powdery substance or in crystalline form. It may also be found in tablet or capsule form when used illicitly.

Comment on solubility

Solubility of 1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine

The solubility of 1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine is influenced by several key factors:

  • Polarity: This compound contains both polar and non-polar components, which can lead to varying solubility in different solvents. Generally, polar solvents like water may dissolve parts of the molecule due to the presence of amine and methoxy groups, while non-polar solvents may facilitate better solubility for the benzodioxole moiety.
  • Hydrogen Bonding: The amine group can participate in hydrogen bonding, which typically enhances solubility in polar solvents. This is especially relevant in aqueous solutions where interactions with water molecules can significantly affect dissolution.
  • Temperature Dependency: Solubility often increases with temperature for most compounds, including amines. Thus, testing the solubility at various temperatures could provide additional insight into its overall solubility profile.

In summary, the solubility of 1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine can be characterized as:

  1. Potentially soluble in polar solvents due to polar functional groups.
  2. More favorable solubility in non-polar solvents due to its hydrophobic character.
  3. Temperature influences the solubility outcomes significantly.

Understanding the solubility characteristics of this compound is crucial for its application in various chemical contexts, as it dictates how the compound will behave in different environments.

Interesting facts

Interesting Facts about 1-(7-Methoxy-1,3-benzodioxol-5-yl)propan-2-amine

1-(7-Methoxy-1,3-benzodioxol-5-yl)propan-2-amine, commonly referred to as a derivative in the amphetamine family, holds a significant place in both organic chemistry and pharmacology. Here are some intriguing facts about this compound:

  • Structural Complexity: This compound features a unique combination of a propan-2-amine backbone with a benzodioxole ring substitution, contributing to its fascinating chemical properties.
  • Psychopharmacological Interest: Compounds related to this structure have been studied for their potential psychoactive effects, often drawing attention for their interactions with serotonin receptors.
  • Synthetic Versatility: The synthetic routes to create this compound can vary, involving various methodologies in organic synthesis, allowing chemists the flexibility to modify its structure for desired outcomes.
  • Research Applications: Due to its structural attributes, this compound is of interest in the development of new medications and understanding drug mechanisms at a molecular level.
  • Regulatory Status: As a compound within the class of phenethylamines, it is essential for chemists and pharmacologists to be aware of the legal implications and regulations governing its use and study.

In summary, 1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine serves as a reminder of the intricate relationships between structure and function in chemical compounds. As one delves into its characteristics, the compound not only enriches our understanding of chemical interactions but also opens up new avenues for research and application in medicinal chemistry.

Synonyms
MMDA
5-Methoxy-3,4-methylenedioxyamphetamine
13674-05-0
3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine
3-Methoxy-4,5-methylenedioxyphenylisopropylamine
RG7FY73ZAA
3-Methoxy-4,5-methylenedioxyamphetamine
3-METHOXY-METHYLENEDIOXYAMPHETAMINE
beta-Methoxy-alpha-methyl-4,5-(methylenedioxy)phenethyl amine
1,3-Benzodioxole-5-ethanamine, 7-methoxy-alpha-methyl
1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine
(+-)-MMDA
DEA No. 7401
Amphetamine, 3,4-methylenedioxy-5-methoxy
1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine
Phenethylamine, alpha-methyl-3-methoxy-4,5-(methylenedioxy)-
(+/-)-MMDA
Phenethylamine, 3-methoxy-alpha-methyl-4,5-(methylenedioxy)-
mmda (drug)
NCGC00247692-01
UNII-RG7FY73ZAA
BRN 1246630
5-methoxy-MDA
1,3-benzodioxole-5-ethanamine, 7-methoxy-alpha-methyl-
MMDA (PSYCHEDELIC)
CHEMBL126506
SCHEMBL1739571
SCHEMBL29827751
DTXSID50860757
YQYUWUKDEVZFDB-UHFFFAOYSA-N
Phenethylamine, 3-methoxy-.alpha.-methyl-4,5-(methylenedioxy)-
(.+/-.)-MMDA
DB01442
NS00018454
C22812
Q4030702
1,3-Benzodioxole-5-ethanamine, 7-methoxy-a-methyl-
(+/-)-5-METHOXY-3,4-METHYLENEDIOXYAMPHETAMINE
2-(7-Methoxy-1,3-benzodioxol-5-yl)-1-methylethylamine
1,3-Benzodioxole-5-ethanamine, 7-methoxy-a-methyl- (9CI)
3-Methoxy-.alpha.-methyl-4,5-methylenedioxyphenethylamine
1,3-Benzodioxole-5-ethanamine, 7-methoxy-alpha-methyl (9CI)
1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-ylazanium chloride
3-METHOXY-.ALPHA.-METHYL-4,5-(METHYLENEDIOXY)PHENETHYLAMINE
3-METHOXY-ALPHA-METHYL-4,5-(METHYLENEDIOXY)PHENETHYLAMINE
Phenethylamine, .alpha.-methyl-3-methoxy-4,5-(methylenedioxy)-
.BETA.-METHOXY-.ALPHA.-METHYL-4,5-(METHYLENEDIOXY)PHENETHYL AMINE