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7-Nitro-3-propionyl-2,3-dihydro-1,4-benzoxazine

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Identification
Molecular formula
C11H10N2O4
CAS number
1082-57-1
IUPAC name
1-(7-nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one
State
State

At room temperature, 7-Nitro-3-propionyl-2,3-dihydro-1,4-benzoxazine exists as a solid. It is stable under standard conditions and is typically handled in its solid form for most applications.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
249.23g/mol
Molar mass
249.2260g/mol
Density
1.2500g/cm3
Appearence

7-Nitro-3-propionyl-2,3-dihydro-1,4-benzoxazine typically appears as a crystalline solid. The crystals may vary in color from pale yellow to orange, owing to the presence of the nitro group which often imparts a distinct coloration.

Comment on solubility

Solubility of 1-(7-nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one

The solubility of 1-(7-nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one can be influenced by a variety of factors, including its chemical structure and the characteristics of the solvent used. Here are some key points to consider:

  • Polarity: This compound contains polar functional groups, which may allow it to dissolve better in polar solvents such as water or alcohols. However, the overall solubility could vary based on the specific solvent properties.
  • Hydrogen Bonding: The presence of nitrogen and oxygen atoms suggests the potential for hydrogen bonding, which may enhance solubility in solvents capable of hydrogen bonding themselves.
  • Molecular Size: As a relatively large organic molecule, the size could hinder solubility in certain solvents, especially those that are non-polar.
  • Temperature: Like many compounds, solubility can increase with temperature, making it beneficial to consider temperature effects in experiments or applications.

While specific solubility data may not be readily available for this compound, typical behaviors of similar structures suggest that it would likely exhibit moderate solubility in polar solvents but may face challenges dissolving in non-polar solvents. Moreover, understanding the solubility behavior of this compound is crucial for its applications in various fields, including pharmaceuticals and organic chemistry.

Interesting facts

Exciting Insights into 1-(7-Nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one

1-(7-Nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one, often referred to as a nitrogenous heterocyclic compound, has piqued the curiosity of scientists and researchers for several reasons:

  • Unique Structure: The compound features a benzoxazine ring system, which is characterized by the presence of both oxygen and nitrogen in the structure. This dual characteristic makes it a subject of interest in medicinal chemistry.
  • Biological Activity: Compounds of this nature are often explored for their potential biological activities, including antimicrobial and anticancer properties. The nitro group can enhance the reactivity of the compound, potentially leading to interesting biological outcomes.
  • Applications in Agriculture: Research has indicated that benzoxazinones are involved in plant defenses, making this compound a candidate for studies in agrochemistry, especially as a natural pesticide or herbicide.
  • Synthetic Pathways: The synthesis of such compounds is not only a fascinating topic but also an excellent way to explore innovative synthetic methods in organic chemistry. It can provide insights into reaction mechanisms and functional group interconversions.

Moreover, the study of 1-(7-nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one can lead to a greater understanding of:

  1. Drug Design: The principles behind structure-activity relationships (SAR) in pharmacology.
  2. Environmental Chemistry: The interactions of such compounds within biological systems and their environmental impact.
  3. Material Science: Its potential application as a building block for novel materials due to its heterocyclic nature.

In summary, the in-depth study of 1-(7-nitro-1,4-dihydro-2,3-benzoxazin-3-yl)propan-1-one is an exciting intersection of organic chemistry, pharmacology, and environmental science that continues to hold great promise for future discoveries.

Synonyms
21038-11-9
BRN 1133402
1H-2,3-BENZOXAZINE, 3,4-DIHYDRO-7-NITRO-3-PROPIONYL-
7-Nitro-3-propionyl-3,4-dihydro-1H-2,3-benzoxazine
DTXSID20175244
RefChem:237285
DTXCID1097735