Carvedilol | Solubility of Things

Identification

Molecular formula

C₂₄H₂₆N₂O₄

CAS number

72956-09-3

IUPAC name

1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

State

At room temperature, carvedilol is a solid compound.

Melting point (Celsius)

114.00

Melting point (Kelvin)

387.15

Boiling point (Celsius)

300.00

Boiling point (Kelvin)

573.15

General information

Molecular weight

406.48g/mol

Molar mass

406.4760g/mol

Density

1.0050g/cm³

Appearence

Carvedilol typically appears as a white to off-white crystalline powder. It is known for its bitter taste.

Comment on solubility

Solubility of 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

The solubility of 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol (C₂₄H₂₆N₂O₄) is influenced by several factors, including its molecular structure and the presence of functional groups. This compound, characterized by its combination of aromatic rings and aliphatic chains, exhibits:

Moderate water solubility: Compounds with large hydrophobic regions often have limited solubility in polar solvents like water.
Higher solubility in organic solvents: Due to the presence of the aromatic carbazole moiety, this compound is more likely to dissolve in non-polar or slightly polar organic solvents such as ethanol or dichloromethane.
Temperature dependence: Like many organic compounds, its solubility can increase with temperature, promoting dissolution.

Overall, the interplay of hydrophobic and hydrophilic segments in the molecular structure plays a pivotal role in determining the solubility behavior of this compound. It is essential to consider the solvent choice based on the intended application to achieve optimal results.

Interesting facts

Interesting Facts about 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

This compound is a fascinating example of a complex organic molecule that blends aromatic structures with functional groups, leading to intriguing potential applications in pharmacology and material science. Here are some highlights:

Chemical Structure: Featuring a ^9H-carbazole unit, this compound incorporates nitrogen-dense rings that have substantial electronic properties, relevant for various chemical processes, including ligands in coordination chemistry.
Pharmacological Relevance: The molecule's unique structure makes it a potential candidate for various therapeutic applications. Research suggests that compounds with similar structures have exhibited neuroprotective and antioxidant properties.
Design Aspect: The molecule showcases a noteworthy design. It features both a carbazole moiety, known for its light-emitting properties, and an ethylamino group, making it versatile for both organic electronics and as a pharmaceutical agent.
Intermolecular Interactions: Due to its intricate functional groups, this compound may engage in complex intermolecular interactions, potentially leading to interesting self-assembly behavior or improved binding affinity to biological targets.
Research Potential: As a chemical structure that combines multiple functional units, it encourages multidisciplinary research approaches, cutting across fields from organic chemistry to pharmacology and even materials science.

In summary, 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol is not just a fascinating compound structurally but also represents the interdisciplinary nature of modern scientific research and its applications.

Synonyms

carvedilol

72956-09-3

Coreg

Dilatrend

Eucardic

Carvedilolum

Kredex

Carvedilolum [Latin]

Dimitone

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

Artist

Querto

BM 14190

BM-14190

SKF 105517

Coronis

Korvasan

Talliton

DQ 2466

1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

DQ-2466

HSDB 7044

(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol

NSC-758694

UNII-0K47UL67F2

SK&F-105517

CHEBI:3441

BM 14.190

BM-14-190

BM-14.190

C07AG02

0K47UL67F2

MFCD00864692

CHEMBL723

SKF-105517

[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine

DTXSID8022747

Carvedilolum (Latin)

NSC 758694

Carvedilol [USAN:USP:INN:BAN:JAN]

1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol

CARVEDILOL (MART.)

CARVEDILOL [MART.]

2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+-)-

CARVEDILOL (USP-RS)

CARVEDILOL [USP-RS]

CARVEDILOL (EP MONOGRAPH)

CARVEDILOL [EP MONOGRAPH]

CARVEDILOL (USP MONOGRAPH)

CARVEDILOL [USP MONOGRAPH]

Coropress

Dibloc

1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol

1-(9H-Carbazol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol

Carvedilol (USAN:USP:INN:BAN:JAN)

1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol

SMR000449280

Artist (TN)

Coreg (TN)

SR-01000759289

carvedilolo

MFCD00869663

1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol

1-(9H-Carbozol-4-yloxy)-3-[[2-(2-methoxy phenoxy)ethyl]amino]-2-propanol

EG-P042

(R)-BM 14190

Carvedilol-methyl-d3

BM14190

Carvedilol (Standard)

Spectrum_001665

CARVEDILOL [MI]

CARVEDILOL [INN]

CARVEDILOL [JAN]

Spectrum2_001673

Spectrum3_001182

Spectrum4_000636

Spectrum5_001436

CARVEDILOL [HSDB]

CARVEDILOL [USAN]

CARVEDILOL [VANDF]

CARVEDILOL [WHO-DD]

SCHEMBL22293

GTPL551

KBioGR_001252

KBioSS_002145

MLS000758299

MLS000759508

MLS001424092

MLS006011886

SPBio_001885

Carvedilol (JP17/USP/INN)

Carvedilol - Bio-X trade mark

DTXCID602747

CARVEDILOL [ORANGE BOOK]

SCHEMBL10082334

SCHEMBL13287211

BDBM25759

HY-B0006R

KBio2_002145

KBio2_004713

KBio2_007281

KBio3_002323

GLXC-03245

HMS2051N03

HMS2089B09

HMS2093E12

HMS3261E15

HMS3269N11

HMS3393N03

HMS3413B14

HMS3655O14

HMS3677B14

HMS3715D15

HMS3750I15

HMS3884E12

Pharmakon1600-01504257

Carvedilol 1.0 mg/ml in Methanol

BCP23386

EX-A5746

HY-B0006

Tox21_500347

BBL029064

MFCD00869664

NSC758694

s1831

STK621453

AKOS005554967

Carvedilol, >=98% (HPLC), solid

AC-1641

BCP9000493

CCG-100917

CCG-207952

CS-1194

DB01136

FC11729

KS-1037

LP00347

NC00167

SB17441

SDCCGSBI-0206771.P002

NCGC00167832-01

NCGC00167832-02

NCGC00167832-03

NCGC00167832-04

NCGC00167832-19

NCGC00261032-01

BC164291

SY129821

SY283162

BCP0726000253

SBI-0206771.P001

DB-055704

DB-057556

DB-057557

C2260

NS00002339

SW197547-3

C06875

D00255

F19969

AB00639903-07

AB00639903-09

AB00639903_10

AB00639903_11

AB00639903_12

L001243

Q412534

SR-01000759289-5

SR-01000759289-6

SR-01000759289-9

BRD-A10977446-001-04-8

BRD-A10977446-001-05-5

BRD-A10977446-001-12-1

BRD-A10977446-001-13-9

BRD-A10977446-001-14-7

BRD-A10977446-011-01-3

BRD-A10977446-045-01-1

Z1515383337

Carvedilol, European Pharmacopoeia (EP) Reference Standard

Carvedilol, United States Pharmacopeia (USP) Reference Standard

1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol

Carvedilol, Pharmaceutical Secondary Standard; Certified Reference Material

(+/-)-1-CARBAZOL-4-YLOXY)-3-((2-(O-METHOXYPHENOXY)ETHYL)AMINO)-2-PROPANOL

(2RS)-1-(9H-Carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol

1-(CARBAZOL-4-YLOXY)-3-((2-(O-METHOXY-PHENOXY)ETHYL)AMINO)-2-PROPANOL

Carvedilol for system suitability, European Pharmacopoeia (EP) Reference Standard

107741-96-8

2-PROPANOL, 1-(9H-CARBAZOL-4-YLOXY)-3-((2-(2-METHOXYPHENOXY)ETHYL)AMINO)-, (+/-)-