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Phenylsemicarbazide

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Identification
Molecular formula
C7H9N3O
CAS number
103-03-7
IUPAC name
1-amino-3-phenyl-urea
State
State

At room temperature, 1-amino-3-phenylurea is typically in the solid state, appearing as a crystalline powder.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
151.17g/mol
Molar mass
151.1670g/mol
Density
1.3489g/cm3
Appearence

1-Amino-3-phenylurea appears as a white to light yellow crystalline solid. It is generally homogeneous in texture with a fine granular appearance.

Comment on solubility

Solubility of 1-amino-3-phenyl-urea

The solubility of 1-amino-3-phenyl-urea is influenced by several factors, including polarity, temperature, and the solvent used. This compound exhibits the following solubility characteristics:

  • Polarity: Due to the presence of the amino group (–NH2) and the urea functional group (–C(=O)NH2), 1-amino-3-phenyl-urea tends to have moderate polarity, allowing it to dissolve in polar solvents.
  • Solvent Compatibility: It is generally soluble in water and alcohols, while it shows lesser solubility in non-polar solvents.
  • Temperature Effects: As is typical with many organic compounds, increased temperatures can enhance solubility; thus, dissolving 1-amino-3-phenyl-urea in warm water may yield better results.

In summary, 1-amino-3-phenyl-urea displays moderate solubility in polar solvents, and factors such as temperature and solvent choice play a crucial role in its dissolving behavior. This compound highlights the delicate balance between chemical structure and solubility dynamics.

Interesting facts

Interesting Facts about 1-Amino-3-phenyl-urea

1-amino-3-phenyl-urea is a unique nitrogen-containing compound that has garnered interest in various fields of chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Pharmaceutical Applications: This compound is known for its potential use in drug formulation. The amino group can interact with biological systems, making it a candidate for various therapeutic agents.
  • Urea Derivatives: As a urea derivative, 1-amino-3-phenyl-urea showcases the versatility of urea as a functional group in organic chemistry. Urea behaves as a versatile scaffold for the design of various bioactive molecules.
  • Intermolecular Interactions: The presence of both an amino group and a phenyl ring gives rise to fascinating intermolecular forces. This property potentially impacts the compound's solubility and reactivity, which can play a crucial role in medicinal chemistry.
  • Research Focus: Ongoing research is looking into the compound’s applications in synthesizing other complex molecules. Its structural characteristics can inspire new approaches in organic synthesis.
  • Historical Context: Urea and its derivatives have been a significant focus of study since the early days of organic chemistry. The exploration of 1-amino-3-phenyl-urea fits within a long tradition of investigating nitrogen-rich compounds.

In summary, the compound 1-amino-3-phenyl-urea is not only noteworthy for its structural properties but also for its potential roles in medicinal chemistry, making it a fascinating subject for both scientific inquiry and application.

Synonyms
4-PHENYLSEMICARBAZIDE
537-47-3
N-Phenylhydrazinecarboxamide
Hydrazinecarboxamide, N-phenyl-
Anilinoformylhydrazine
Hydrazinecarboxanilide
Anilinocarbonylhydrazine
Phenylaminocarbonylhydrazine
BPU96SX57A
EINECS 208-669-2
NSC-231527
AI3-61985
DTXSID80201957
4-PHENYLSEMICARBAZIDE [MI]
NSC 231527
DTXCID10124448
208-669-2
1-Amino-3-phenylurea
3-amino-1-phenylurea
MFCD00007590
Semicarbazide, 4-phenyl-
1-amino-3-phenyl-urea
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a
UNII-BPU96SX57A
4-Phenyl semicarbazide
N-phenylhydrazine carboxamide
N-Phenylhydrazinecarboxamide #
SCHEMBL712280
CHEBI:168436
HMS1782N01
ALBB-002786
STR03408
BBL036427
NSC231527
STK500545
AKOS000121537
SB73811
NCGC00331598-01
SY045865
DB-052393
CS-0100039
NS00032833
P0228
EN300-16997
D91930
AB01326528-02
Q27274801
Z56855648
Chondroitin sulphate e (galnac4,6Dis-glca), precursor 5a
Chondroitin sulfuric acid e (galnac4,6Dis-glca), precursor 5a
Chondroitin sulphuric acid e (galnac4,6Dis-glca), precursor 5a
InChI=1/C7H9N3O/c8-10-7(11)9-6-4-2-1-3-5-6/h1-5H,8H2,(H2,9,10,11