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Cimetidine

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Identification
Molecular formula
C10H16Cl2N6S
CAS number
51481-61-9
IUPAC name
1-[amino-(3,4-dichloroanilino)methylene]-2-isopropyl-guanidine
State
State

At room temperature, cimetidine is a solid substance in the form of a crystalline powder.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
513.00
Boiling point (Kelvin)
786.15
General information
Molecular weight
252.34g/mol
Molar mass
252.3440g/mol
Density
1.1682g/cm3
Appearence

Cimetidine is a white or slightly yellow, crystalline powder.

Comment on solubility

Solubility Overview

The compound 1-[amino-(3,4-dichloroanilino)methylene]-2-isopropyl-guanidine exhibits intriguing solubility characteristics due to its complex structure. Understanding its solubility can provide insights into its potential applications and behavior in various environments.

Factors Influencing Solubility

  • Polarity: The presence of both amino groups and the guanidine moiety suggests a degree of polarity, which can influence solubility in polar solvents like water.
  • Substituents: The 3,4-dichloroanilino group may introduce steric hindrance, potentially affecting how well the compound interacts with solvents.
  • Temperature: Solubility often varies with temperature; this compound may show increased solubility at elevated temperatures due to enhanced kinetic energy of molecules.

General Behavior

It is expected that this compound would have limited solubility in non-polar solvents due to its relatively polar functional groups. In contrast, one might find better solubility in
solvents such as:

  • Dimethyl sulfoxide (DMSO)
  • Ethanol
  • Water (to a lesser extent)

In conclusion, while the precise solubility of 1-[amino-(3,4-dichloroanilino)methylene]-2-isopropyl-guanidine may be dependent on several factors, it is likely to display greater affinity for polar solvents. Exploring these interactions can yield valuable information regarding the compound's reactivity and usability in chemical processes.

Interesting facts

Interesting Facts about 1-[amino-(3,4-dichloroanilino)methylene]-2-isopropyl-guanidine

This intriguing compound is notable for its multifaceted role in various scientific fields, particularly medicinal chemistry. Here are some enlightening points to consider:

  • Biological Significance: Composed of a guanidine core, this compound has been investigated for its potential pharmacological properties, particularly in the regulation of blood glucose levels.
  • Structure-Activity Relationship: The introduction of the 3,4-dichloroanilino group plays a crucial role in enhancing the activity of the molecule, highlighting the importance of chemical modifications in drug design.
  • Research Applications: Studies have suggested its utility in diabetes management, making it a subject of interest for researchers striving to develop innovative therapeutic agents.
  • Mechanism of Action: While the exact mechanisms remain under exploration, compounds like this have the potential to influence specific pathways involved in insulin signaling.
  • Synergistic Properties: When combined with other therapies, the unique properties of this compound could lead to synergistic effects, improving treatment efficacy for various conditions.

As you delve into the fascinating world of chemical compounds, the study of 1-[amino-(3,4-dichloroanilino)methylene]-2-isopropyl-guanidine serves as a prime example of how tinkering with molecular architecture can lead to groundbreaking advancements in healthcare and medicine.

Synonyms
N-(3,4-Dichlorophenyl)-N'-(1-methylethyl)imidodicarbonimidic Diamide Hydrochloride;1-(3,4-Dichlorophenyl)-5-isopropylbiguanide; Chloroproguanil Hydrochloride; N1-3,4-Dichlorophenyl-N5-isopropyldiguanide Hydrochloride; M 5943;
M 5943
AC9294
MFCD00866200
SY251559
NS00032828
Q5103229