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Di-n-butyl phosphoramidate

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Identification
Molecular formula
C8H20NO3P
CAS number
4546-33-2
IUPAC name
1-[amino(butoxy)phosphoryl]oxybutane
State
State

At room temperature, di-n-butyl phosphoramidate is a liquid.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
209.25g/mol
Molar mass
209.2480g/mol
Density
0.9700g/cm3
Appearence

Di-n-butyl phosphoramidate typically appears as a colorless liquid. It may have a weak characteristic odor. The physical appearance can vary slightly depending on the level of purity and any stabilizers that may be added.

Comment on solubility

Solubility of 1-[amino(butoxy)phosphoryl]oxybutane

Understanding the solubility of 1-[amino(butoxy)phosphoryl]oxybutane is essential for its applications in various chemical processes. The solubility of a compound is influenced by several factors, including:

  • Molecular structure: The presence of functional groups such as the -NH2 (amino) and -O (ether) can significantly affect solubility.
  • Polarity: This compound features both polar and non-polar regions, which affects its interaction with solvents. Generally, polar compounds are more soluble in polar solvents.
  • Temperature: As with many compounds, solubility can increase with temperature, allowing for greater dissolution in solvents at elevated temperatures.

It is essential to note that 1-[amino(butoxy)phosphoryl]oxybutane is likely to have moderate solubility in water due to the influence of the amino and ether groups. According to general solubility principles: "like dissolves like," meaning this compound would find better solubility in polar solvents than in purely non-polar environments.

In summary, while detailed solubility data requires empirical research, the preliminary understanding of its molecular features suggests that 1-[amino(butoxy)phosphoryl]oxybutane may exhibit moderate solubility characteristics, especially in polar solvents.

Interesting facts

Interesting Facts about 1-[amino(butoxy)phosphoryl]oxybutane

1-[amino(butoxy)phosphoryl]oxybutane is a fascinating compound that plays a significant role in various fields of chemistry and biology. Here are some intriguing aspects you might find interesting:

  • Phosphorylation Reactions: This compound features a phosphoryl group, which is essential in many biochemical processes. Phosphorylation reactions are critical for energy transfer in cells and are involved in regulating enzymes and proteins.
  • Amine Functional Group: The presence of an amino group in its structure makes 1-[amino(butoxy)phosphoryl]oxybutane a potential candidate for various types of chemical reactions, especially those involving nucleophilic substitutions.
  • Potential Applications: Compounds like this one can serve as intermediates in the synthesis of pharmaceuticals, agrochemicals, and other bioactive molecules. Specifically, it may find use in creating more effective drugs through targeted delivery systems.
  • Versatility: The butoxy group contributes to the compound's hydrophobic characteristics, which can influence its biological interactions and solubility in biological membranes.

This compound showcases the intricate relationships between chemical structure and biological function. As we continue to explore the realms of organic and medicinal chemistry, understanding the unique properties of compounds like 1-[amino(butoxy)phosphoryl]oxybutane becomes ever more important. It reminds us that even small modifications in molecular architecture can lead to significant changes in function!

Synonyms
Dibutyl phosphoramidate
PHOSPHORAMIDIC ACID, DIBUTYL ESTER
870-52-0
Di-n-butyl phosphoroamidate
NSC-62043
NSC 62043
BRN 1707479
Dibutylphosphoramidate
di-n-butyl phosphoramidate
WLN: 4OPZO&O4
6G5HQ5Y7PX
4-01-00-01534 (Beilstein Handbook Reference)
SCHEMBL617402
DTXSID40236048
NSC62043