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1-(Aziridin-1-yl)ethanone

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Identification
Molecular formula
C4H7NO
CAS number
4709-92-0
IUPAC name
1-(aziridin-1-yl)ethanone
State
State

At room temperature, 1-(Aziridin-1-yl)ethanone is in a liquid state.

Melting point (Celsius)
-63.00
Melting point (Kelvin)
210.00
Boiling point (Celsius)
118.50
Boiling point (Kelvin)
391.65
General information
Molecular weight
85.11g/mol
Molar mass
85.1110g/mol
Density
1.0460g/cm3
Appearence

1-(Aziridin-1-yl)ethanone is typically found as a colorless liquid. Due to its aziridine ring, it may have a somewhat sweet odor but can be irritating. It is sensitive to air and moisture, appearing clear in its pure form.

Comment on solubility

Solubility of 1-(aziridin-1-yl)ethanone

1-(aziridin-1-yl)ethanone, a compound characterized by its unique structure, exhibits intriguing solubility properties. Understanding its solubility helps in predicting its behavior in various chemical environments. Here are some key points to consider:

  • Polar Nature: Due to the presence of the aziridine ring and the carbonyl group, 1-(aziridin-1-yl)ethanone is likely to be a polar compound.
  • Solvent Compatibility: It is generally soluble in polar solvents such as water and alcohols, making it suitable for reactions in such media.
  • Limited Solubility: In non-polar solvents, its solubility might be significantly reduced, indicating a clear preference for polar environments.

To summarize, the solubility of 1-(aziridin-1-yl)ethanone can be described as:

  1. Moderately soluble in water.
  2. Soluble in organic polar solvents.
  3. Insufficiently soluble in non-polar solvents.

This solubility profile reflects the compound's interactions at the molecular level, highlighting its predominant behavior in polar settings.

Interesting facts

Exploring 1-(aziridin-1-yl)ethanone

1-(aziridin-1-yl)ethanone is a fascinating organic compound that belongs to the class of aziridines, which are three-membered cyclic amines. These compounds are known for their unique reactivity and have garnered significant interest in the fields of organic chemistry and medicinal chemistry due to their versatile applications. Here are some intriguing insights about this compound:

  • Cyclic Structure: The presence of the aziridine ring imparts distinctive properties to 1-(aziridin-1-yl)ethanone, making it a valuable intermediate in synthesizing various organic compounds.
  • Pharmaceutical Relevance: Aziridines are known for their potential as drug candidates, serving as building blocks for the synthesis of biologically active molecules. This raises the compound's profile within the biomedical research community.
  • Reactivity: The strain in the three-membered aziridine structure contributes to its high reactivity, allowing for a range of transformation reactions, including ring-opening and substitution. This makes it useful in organic synthesis.
  • Importance in Polymer Chemistry: 1-(aziridin-1-yl)ethanone can be utilized in the production of functional polymers, contributing to advancements in material science.
  • Research Potential: As an emerging compound of interest, ongoing studies are exploring its role in drug development, specifically as it relates to therapeutic candidates in treating various diseases.

In summary, 1-(aziridin-1-yl)ethanone not only showcases the intriguing aspects of aziridine chemistry but also highlights the vast potential for these compounds to influence future research and applications in both organic synthesis and pharmacology. A quote often echoed in the scientific community resonates here: "Innovations often come from the least expected corners of chemistry."

Synonyms
1-Acetylaziridine
N-Acetylethyleneimine
460-07-1
Acetylethylenimine
N-Acetylethylenimine
N-Acetylaziridine
AZIRIDINE, 1-ACETYL-
1-(aziridin-1-yl)ethanone
Acetylethylenimide
EINECS 207-301-8
AO0886WFZU
BRN 0105879
Ethanone, 1-(1-aziridinyl)-
AI3-50406
1-ACETYLETHYLENIMINE
DTXSID3060035
5-20-01-00038 (Beilstein Handbook Reference)
J38.345G
N-Acetylethylenimine, contains ~40% benzene
N-Acetylethylenimine, contains ~40% Cyclohexane
1-(1-Aziridinyl)ethanone
UNII-AO0886WFZU
1-(1-Aziridinyl)ethanone; 1-Acetylaziridine; Acetylethylenimide; N-Acetylaziridine;
DTXCID5040461
1-(aziridin-1-yl)ethan-1-one
AKOS006228846
NS00031577
N-Acetylethylenimine, contains ~40per cent benzene
Q26840998
207-301-8