Skip to main content

1-(Benzenesulfonyl)aziridine

ADVERTISEMENT
Identification
Molecular formula
C8H9NO2S
CAS number
14030-90-1
IUPAC name
1-(benzenesulfonyl)aziridine
State
State

At room temperature, 1-(Benzenesulfonyl)aziridine is in a solid state, generally found as a crystalline powder.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
183.22g/mol
Molar mass
183.2170g/mol
Density
1.3497g/cm3
Appearence

1-(Benzenesulfonyl)aziridine, also known simply as benzenesulfonylaziridine, is typically found as a crystalline solid. The compound’s crystals are fine and can range from colorless to pale yellow, depending on purity and storage conditions.

Comment on solubility

Solubility of 1-(benzenesulfonyl)aziridine

1-(benzenesulfonyl)aziridine, a chemical compound featuring a unique aziridine ring, presents interesting solubility characteristics. Understanding the solubility of this compound in various solvents can provide insight into its potential applications and behavior in different environments.

General Solubility Characteristics

The solubility of 1-(benzenesulfonyl)aziridine can vary significantly depending on the solvent used. Here are some key points regarding its solubility:

  • Polar Solvents: 1-(benzenesulfonyl)aziridine tends to be more soluble in polar solvents such as water and dimethyl sulfoxide (DMSO). The presence of the sulfonyl group enhances its interactions with polar molecules.
  • Apolar Solvents: In contrast, this compound may exhibit lower solubility in non-polar solvents like hexane or toluene, where the aziridine structure's polarity is less compatible.
  • Temperature Influence: The solubility can also be temperature-dependent; higher temperatures often increase solubility due to enhanced molecular movement and stronger interactions.

Practical Implications

For practical applications, understanding the solubility of 1-(benzenesulfonyl)aziridine is crucial:

  • In chemical synthesis, the chosen solvent can directly affect reaction rates and products.
  • The solubility profile can aid in formulation development in industries such as pharmaceuticals, where solubility impacts bioavailability.

In conclusion, the solubility of 1-(benzenesulfonyl)aziridine is influenced by various factors including the nature of the solvent, temperature, and its inherent structural properties. Identifying suitable solvents for this compound is essential for its efficient use in scientific and industrial applications.

Interesting facts

Interesting Facts about 1-(Benzenesulfonyl)aziridine

1-(Benzenesulfonyl)aziridine is a fascinating compound that belongs to the class of aziridines, which are three-membered cyclic amines. This compound is characterized by the incorporation of a benzenesulfonyl group, which greatly influences its reactivity and applications in organic chemistry. Here are some intriguing aspects of this compound:

  • Reactivity: The presence of the sulfonyl group enhances the electrophilic character of the aziridine ring, making it a useful intermediate in various organic transformations.
  • Strategies in Synthesis: 1-(Benzenesulfonyl)aziridine can be synthesized through methods such as nucleophilic substitution or ring-opening reactions, showcasing the versatility of aziridine chemistry.
  • Applications: This compound can be used in the synthesis of more complex molecules, particularly in the design of pharmacologically active compounds and as a building block for drug discovery.
  • Biological Significance: Aziridines are known for their biological activity, and the sulfonyl modification can alter their interactions with biological targets, which is an area of active research.
  • Innovation: The unique structural features of 1-(benzenesulfonyl)aziridine make it a subject of interest in developing new synthetic methodologies and exploring its potential in asymmetric synthesis.

As noted by chemists in the field, "The fine balance between stability and reactivity in aziridines allows for innovative approaches in synthetic chemistry." This makes 1-(benzenesulfonyl)aziridine a noteworthy compound to study, whether for its theoretical implications or practical applications.

In conclusion, the exploration of 1-(benzenesulfonyl)aziridine not only enriches our understanding of aziridine chemistry but also opens doors for advancements in the synthesis of complex organic molecules. Its role as a versatile reagent continues to inspire further research and innovation in the field.

Synonyms
10302-15-5
1-(PHENYLSULFONYL)AZIRIDINE
Aziridine, 1-(phenylsulfonyl)-
N-Benzenesulfonylaziridine
HSDB 6153
EINECS 233-676-2
AI3-50705
DTXSID8065030
NBenzenesulfonylaziridine
Aziridine, 1(phenylsulfonyl)
DTXCID6032778
1-(benzenesulfonyl)aziridine
1-(Phenylsulphonyl)aziridine
Aziridine,1-(phenylsulfonyl)-
phenylsulfonylaziridine
ZTR68NHJ9T
SCHEMBL735657
SCHEMBL3830424
SCHEMBL3830427
AXWKGBIMVDATLR-UHFFFAOYSA-N
AKOS000278673
NS00023201
EN300-1456576