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1-Benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine

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Identification
Molecular formula
C25H28N2O2
CAS number
.166487-38-3
IUPAC name
1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine
State
State
The compound is typically a crystalline solid at room temperature.
Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
491.80
Boiling point (Kelvin)
764.95
General information
Molecular weight
386.51g/mol
Molar mass
386.4770g/mol
Density
1.1950g/cm3
Appearence

1-Benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine appears as an off-white to pale yellow solid at room temperature.

Comment on solubility

Solubility of 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine

The solubility of 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine can be influenced by various factors. Understanding its solubility is crucial in applications such as drug formulation and chemical synthesis. Here are some key points to consider:

  • Polar vs Non-Polar Solvents: This compound, featuring both aromatic and piperazine moieties, may exhibit differential solubility characteristics in polar versus non-polar solvents. Generally, such compounds are more soluble in organic solvents like methanol and dichloromethane.
  • Hydrophilicity and Hydrophobicity: With the presence of the benzodioxole group, the compound could exhibit a degree of hydrophilicity, but the larger hydrophobic benzhydryl substituent may counterbalance this, affecting overall solubility.
  • Temperature Influence: Solubility often increases with temperature, meaning conditions such as stirring and heating could enhance the dissolution of this compound in a solvent system.
  • pH Levels: As a piperazine derivative, the solubility may also be affected by the pH of the solvent, considering that the basic nature of the piperazine group can lead to protonation at lower pH, affecting its solubility profile.

In summary, the solubility of 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine is a complex interplay of structural features and environmental conditions. Understanding these can enable more effective applications and optimizations in various chemical contexts.

Interesting facts

Interesting Facts about 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine

This compound, known as 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine, is a fascinating example of a piperazine derivative that showcases the intricate relationship between structure and function in medicinal chemistry.

Chemical Structure and Functionality

With its unique and complex structure, this compound boasts several noteworthy features:

  • Piperazine Ring: The piperazine moiety is a well-known scaffold in pharmacology, often displaying various biological activities.
  • Phenyl and Benzodioxole Groups: The presence of the benzhydryl and benzodioxole groups contributes to the compound's potential for binding to biological targets, which could enhance its effectiveness as a therapeutic agent.

Potential Applications

This compound’s structural novelty sparks interest for potential applications in various fields:

  • Drug Development: Given its unique architecture, it is worth investigating the compound's properties in drug discovery processes.
  • Psychopharmacology: The piperazine structure is often associated with psychoactive effects, making it a compelling candidate for research in mental health treatments.

Research and Development

As a scientist or a chemistry student, one might ponder the following:

  • What novel pathways does this compound influence in the body?
  • How does the interaction of the benzodioxole moiety play a role in its pharmacological properties?

In conclusion, the compound 1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine exemplifies the elegance of chemical complexity and its potential implications in the realm of medicinal chemistry. Its multifaceted structure invites further exploration, representing a small piece of the vast puzzle in drug research.

Synonyms
Medibazine
53-31-6
1-(Diphenylmethyl)-4-piperonylpiperazine
7NFK89B690
S-4105
s4105
Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-(diphenylmethyl)-
DTXSID70201042
RefChem:156224
DTXCID70123533
200-168-7
Vialibran
Medibazina
Medibazine [INN:DCF]
1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine
MEDIBAZINE HYDROCHLORIDE
S 4105
Medibazina [DCIT]
Medibazinum
Medibazinum [INN-Latin]
10F3RUK41T
EINECS 200-168-7
Benzhydryl-1-piperonyl piperazine
22193-78-8
BRN 0901009
Medibazin
UNII-7NFK89B690
4105 S
Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-(diphenylmethyl)-, hydrochloride (1:1)
MEDIBAZINE [MI]
Piperazine, 1-diphenylmethyl-4-piperonyl-
MEDIBAZINE [INN]
UNII-10F3RUK41T
SCHEMBL308996
CHEMBL2104758
CHEBI:135607
ORAUEDBBTFLQSK-UHFFFAOYSA-N
1-BENZHYDRYL-4-PIPERONYLPIPERAZINE
DS-002658
NS00032712
Q27268616
1-(1,3-benzodioxol-5-ylmethyl)-4-(diphenylmethyl)piperazine