1-(Benzothiophen-3-yl)-2-(dimethylamino)ethanol

Identification

Molecular formula

C₁₂H₁₅NO₂S

CAS number

115787-50-3

IUPAC name

1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol

State

The compound is in a solid state at room temperature.

Melting point (Celsius)

105.00

Melting point (Kelvin)

378.15

Boiling point (Celsius)

337.20

Boiling point (Kelvin)

610.35

General information

Molecular weight

221.32g/mol

Molar mass

221.3070g/mol

Density

1.1582g/cm³

Appearence

This compound appears as a pale yellow to off-white solid under normal conditions.

Comment on solubility

Solubility of 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol

The solubility of 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol in various solvents can provide crucial insights into its chemical behavior and potential applications. Understanding solubility is key to many aspects including:

Chemical Reactivity: Solubility influences how readily the compound can participate in chemical reactions.
Formulation Considerations: The solubility in solvent systems determines its usability in pharmaceuticals and other products.
Toxicology and Bioavailability: Solubility affects the absorption of the compound in biological systems, critical for therapeutic efficacy.

Generally, 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol is expected to exhibit moderate solubility in polar solvents due to the presence of the amino alcohol functional group. However, its hydrophobic benzothiophen moiety may limit solubility in highly polar solvents. Therefore, the following points should be considered:

Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).
Temperature Dependence: Solubility may increase with temperature, commonly observed in many organic compounds.
pH Influence: The ionization of the amine group may be impacted by the pH of the solution, altering solubility characteristics.

The overall solubility profile of this compound is essential for optimizing its use across various fields, from drug formulation to materials science. "Solubility is not just a property; it's the pathway to application."

Interesting facts

Interesting Facts about 1-(Benzothiophen-3-yl)-2-(dimethylamino)ethanol

This compound, known as 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol, is a fascinating organic molecule that features a unique combination of functional groups, making it a subject of research in pharmacology and organic synthesis. Here are some engaging insights:

Structural Diversity: The presence of both a benzothiophene moiety and a dimethylamino group contributes to the structural complexity of this compound. Benzothiophene is a polycyclic aromatic compound that plays an important role in many biological activities.
Biological Significance: Compounds similar to this one have been investigated for their potential pharmacological effects. Their ability to interact with biological targets gives rise to interest in their application as pharmaceuticals.
Synthesis Pathways: The synthesis of 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol often involves reactions that form carbon-carbon and carbon-nitrogen bonds, providing valuable experiences in synthetic organic chemistry.
Potential Applications: The pharmacological relevance of compounds with dimethylamino groups is crucial in the design of new drugs, particularly as they can influence the compound’s bioactivity and solubility.
Research Implications: Several academic studies are exploring derivatives of this compound to enhance its efficacy or identify novel actions, illustrating the ongoing interest in its chemical properties and potential uses.

In conclusion, 1-(benzothiophen-3-yl)-2-(dimethylamino)ethanol exemplifies the intersection of synthetic chemistry and pharmacology. As scientists continue to investigate its properties and effects, this compound stands as a testament to the creativity and complexity found in the world of chemical science.