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1-(benzothiophen-3-yl)-2-morpholino-ethanol

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Identification
Molecular formula
C15H17NO2S
CAS number
153899-47-9
IUPAC name
1-(benzothiophen-3-yl)-2-morpholino-ethanol
State
State

Under standard laboratory conditions, 1-(benzothiophen-3-yl)-2-morpholino-ethanol is found in a solid state. It is stable if stored properly, away from moisture and excessive heat.

Melting point (Celsius)
103.50
Melting point (Kelvin)
376.65
Boiling point (Celsius)
454.20
Boiling point (Kelvin)
727.35
General information
Molecular weight
261.37g/mol
Molar mass
261.3520g/mol
Density
1.3370g/cm3
Appearence

The compound typically appears as a crystalline solid under standard conditions. The color may vary from off-white to pale yellow, depending on purity and specific batch characteristics.

Comment on solubility

Solubility of 1-(benzothiophen-3-yl)-2-morpholino-ethanol

The solubility of 1-(benzothiophen-3-yl)-2-morpholino-ethanol can be quite intriguing due to the unique structural features of the compound. This compound, containing both a benzothiophene moiety and a morpholine ring, suggests the following solubility characteristics:

  • Solvent Compatibility: It is expected to exhibit solubility in a range of organic solvents, particularly those that are polar, such as ethanol and methanol.
  • Hydrophilicity vs. Hydrophobicity: The morpholine portion is likely to contribute to increased hydrophilicity, while the benzothiophene group may introduce some hydrophobic properties.
  • Potential Applications: Understanding its solubility is essential for formulating this compound in pharmaceuticals and other applications where solubility can affect bioavailability and efficacy.

As a general rule, solubility is influenced by factors such as temperature, pH, and the presence of other solutes. Solubility testing in different media can provide valuable insights into how to best utilize 1-(benzothiophen-3-yl)-2-morpholino-ethanol in practical applications.

In conclusion, the solubility profile of this compound is governed by a delicate balance of its chemical structure, which warrants thorough investigation to maximize its utility.

Interesting facts

Interesting Facts about 1-(Benzothiophen-3-yl)-2-morpholino-ethanol

1-(Benzothiophen-3-yl)-2-morpholino-ethanol is a fascinating compound that blends the unique features of both benzothiophene and morpholine. Here are some particularly intriguing aspects of this compound:

  • Structural Complexity: This compound showcases an interesting structural combination, featuring a benzothiophene moiety, which is known for its aromatic properties, linked to a morpholine ring that introduces versatility in reactivity.
  • Biological Significance: Compounds containing benzothiophene rings are often studied for their potential pharmaceutical applications, including anti-inflammatory and anti-cancer activities. The morpholino group may enhance the biological activity by improving solubility and bioavailability.
  • Electronic Properties: The presence of sulfur in the benzothiophene structure contributes to unique electronic properties, making this compound interesting for organic electronics research, particularly in the development of organic semiconductors.
  • Potential Applications: Beyond medicinal chemistry, this compound could serve as a building block for synthesizing more complex organic materials, such as dyes or light-emitting compounds, owing to its conjugated system.
  • Synthetic Pathways: The synthesis of 1-(benzothiophen-3-yl)-2-morpholino-ethanol often involves multi-step reactions, which can teach students valuable synthetic strategies and techniques in organic chemistry.

As a quote from famous chemist Linus Pauling goes, "The best way to have a good idea is to have a lot of ideas." Studying compounds like 1-(benzothiophen-3-yl)-2-morpholino-ethanol can inspire new ideas and developments in various fields of chemistry and materials science.

Synonyms
1-(1-benzothien-3-yl)-2-(4-morpholinyl)ethanol
1-(1-benzothiophen-3-yl)-2-morpholin-4-ylethanol
Oprea1_310122
AE-534/30057014
CHEMBL1907574