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Isatin

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Identification
Molecular formula
C8H5NO2
CAS number
91-56-5
IUPAC name
1-benzoylindoline-2,3-dione
State
State

At room temperature, isatin is in a solid state. It is a stable compound that can be stored under standard laboratory conditions.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.00
Boiling point (Celsius)
384.00
Boiling point (Kelvin)
657.00
General information
Molecular weight
147.14g/mol
Molar mass
147.1410g/mol
Density
1.4220g/cm3
Appearence

Isatin is typically a solid compound that appears as an orange-red crystalline powder. It is known for its vibrant color and is often used in dyeing applications.

Comment on solubility

Solubility of 1-benzoylindoline-2,3-dione

1-benzoylindoline-2,3-dione, known for its remarkable chemical structure, exhibits interesting solubility characteristics that are noteworthy for various applications. Its solubility can be summarized as follows:

  • Solvent Compatibility: This compound is primarily soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), making it suitable for various organic syntheses.
  • Limited Water Solubility: 1-benzoylindoline-2,3-dione shows a low solubility in water, which is common for many organic compounds owing to their hydrophobic characteristics.
  • Temperature Influence: Solubility may increase with temperature, so conducting experiments at elevated temperatures can yield better results in solvent systems.

In summary, the solubility of 1-benzoylindoline-2,3-dione is influenced by its structure, favoring organic solvents while remaining relatively insoluble in water. When working with this compound, it is essential to choose the right solvent to enhance its applicability in various chemical reactions.

Interesting facts

Exploring 1-Benzoylindoline-2,3-dione

1-Benzoylindoline-2,3-dione is a fascinating compound that belongs to the class of indole derivatives. Here are some intriguing facts about this compound:

  • Synthetic Versatility: This compound is often used as a precursor in organic synthesis, highlighting its ability to serve as a building block for more complex molecules.
  • Biological Activity: Researchers have found that indole derivatives, including this compound, play significant roles in various biological activities. They have been investigated for their potential as pharmaceuticals, showcasing their importance in drug discovery.
  • Potential Applications: The optical properties and reactivity of 1-benzoylindoline-2,3-dione make it an interesting candidate for applications in dyes, pigments, and other materials.
  • Mechanistic Insights: Its structure offers insights into the mechanisms of reactions involving electrophiles and nucleophiles, making it a valuable study subject in reaction mechanism courses.

As a chemistry student or practicing scientist, understanding compounds like 1-benzoylindoline-2,3-dione opens up avenues for research in organic synthesis, medicinal chemistry, and materials science. As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." The diversity of applications for such compounds certainly provides a rich ground for exploration!

Synonyms
N-Benzoylisatin
1-Benzoyl-1H-indole-2,3-dione
28284-05-1
1-Benzoylisatin
1-Benzoyl-indole-2,3-dione
1H-Indole-2,3-dione, 1-benzoyl-
NSC 127078
BRN 0016540
INDOLE-2,3-DIONE, 1-BENZOYL-
NSC-127078
DTXSID60182533
4-21-00-05000 (Beilstein Handbook Reference)
UNII-276X936194
276X936194
RefChem:162910
DTXCID00105024
1H-Indole-2,3-dione, 1-benzoyl-(9CI)
1-Benzoylindoline-2,3-dione
CHEMBL118830
1-benzoyl-2,3-dihydro-1H-indole-2,3-dione
NSC127078
1H-Indole-2,3-dione, 1-benzoyl- (9CI)
SCHEMBL10353187
YKLHWMNKDGZBAX-UHFFFAOYSA-N
BDBM50133616
STK051154
AKOS000618468
1-(phenylcarbonyl)-1H-indole-2,3-dione
WL-148210
SR-01000321021
SR-01000321021-1