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1-Benzyl-1,2,4-triazole

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Identification
Molecular formula
C9H9N3
CAS number
6947-16-4
IUPAC name
1-benzyl-1,2,4-triazole
State
State

At room temperature, 1-Benzyl-1,2,4-triazole is a solid.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
160.19g/mol
Molar mass
160.1950g/mol
Density
1.1360g/cm3
Appearence

1-Benzyl-1,2,4-triazole typically appears as a colorless to pale yellow crystalline solid or powder. It is often found in the form of small crystals.

Comment on solubility

Solubility of 1-benzyl-1,2,4-triazole

1-benzyl-1,2,4-triazole is a chemical compound that exhibits interesting solubility characteristics. Its solubility can be influenced by several factors:

  • Polarity: The presence of a benzyl group imparts a level of non-polar characteristics, which can hinder solubility in highly polar solvents.
  • Solvent Type: This compound is generally more soluble in organic solvents, such as ethanol and acetone, compared to water.
  • Temperature: Like many organic compounds, solubility in various solvents can increase with temperature, suggesting enhanced solubility in heat.

As noted in various studies, 1-benzyl-1,2,4-triazole tends to be moderately soluble in most organic solvents but shows limited solubility in water. The ability to dissolve in different solvents is crucial for its application in various chemical processes and formulations.

In summary, while 1-benzyl-1,2,4-triazole may not be universally soluble, its solubility profile in organic media highlights its versatility and importance in chemical research and applications. Remember, "the solvent matters!"

Interesting facts

Interesting Facts about 1-benzyl-1,2,4-triazole

1-benzyl-1,2,4-triazole is an intriguing compound that has gained attention in various fields, including medicinal chemistry and agricultural applications. Here are some captivating aspects of this compound:

  • Triazole Ring System: The presence of the triazole ring is noteworthy. This five-membered heterocyclic compound finds extensive usage in pharmaceuticals, as it often exhibits antifungal, antibacterial, and anticancer properties.
  • Pharmacological Potential: Compounds containing triazole moieties, including 1-benzyl-1,2,4-triazole, are known for their ability to inhibit specific enzymes and receptors. This action opens up possibilities for drug development, particularly in targeting various disease pathways.
  • Versatility in Synthesis: The synthetic routes to produce 1-benzyl-1,2,4-triazole can vary widely, allowing chemists to explore different methodologies. This adaptability makes it an interesting target for organic synthesis, appealing to both academic research and industrial applications.
  • Role in Agriculture: Beyond its medicinal properties, triazole derivatives, including this compound, are investigated for their effectiveness in agricultural practices, particularly as fungicides, to help protect crops from fungal diseases.

As chemists delve deeper into the properties and potential applications of 1-benzyl-1,2,4-triazole, the compound continues to reveal exciting opportunities for innovation in both health and agricultural sciences.

Synonyms
1-Benzyl-1,2,4-triazole
1-Benzyl-1H-1,2,4-triazole
6085-94-5
1H-1,2,4-Triazole, 1-(phenylmethyl)-
1H-1,2,4-TRIAZOLE, 1-BENZYL-
L-22080
CHEMBL1825021
BRN 0118646
1-Benzyl-s-triazole
5-26-01-00148 (Beilstein Handbook Reference)
SCHEMBL2917482
DTXSID00209692
WLZ3166
BDBM50351860
AKOS008967340
N-(phenylmethyl)-1H-1,2,4-triazole
1-(phenylmethyl)-1H-1,2,4-triazole
AC-14377
CS-0432874
E84645
EN300-106661
SR-01000388915
SR-01000388915-1
Z57161818
InChI=1/C9H9N3/c1-2-4-9(5-3-1)6-12-8-10-7-11-12/h1-5,7-8H,6H