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1-Benzylpiperidine

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Identification
Molecular formula
C18H23NO
CAS number
60519-55-7
IUPAC name
1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine
State
State

At room temperature, 1-Benzylpiperidine is typically a solid. Its melting point is relatively low, allowing it to exist just above room temperature as either a solid or very viscous liquid.

Melting point (Celsius)
36.00
Melting point (Kelvin)
309.15
Boiling point (Celsius)
356.00
Boiling point (Kelvin)
629.15
General information
Molecular weight
209.31g/mol
Molar mass
209.3140g/mol
Density
1.1050g/cm3
Appearence

1-Benzylpiperidine is a crystalline solid. It can also be described as a white to off-white powder, depending on the purity and specific manufacturing processes employed. Its detailed structural characteristics contribute to its relatively complex appearance among organic compounds.

Comment on solubility

Solubility of 1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine

When considering the solubility of 1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine, several factors come into play due to its complex structure. This compound, which possesses both aromatic and aliphatic features, demonstrates unique solubility characteristics:

  • Polarity: The dioxolane ring introduces some polar character, which may enhance solubility in polar solvents.
  • Aromatic interactions: The presence of the diphenyl groups can facilitate solubility in organic solvents, reflecting a tendency to dissolve in non-polar or weakly polar environments.
  • Hydrogen bonding: If the solvent has the ability to hydrogen bond, such as alcohols or ethers, the solubility may be improved.

Overall, the solubility of this compound can be described as potentially moderate, heavily dependent on the solvent choice. It is likely to be more soluble in organic solvents like ethyl acetate or dichloromethane than in water. As with many organic compounds, the rule of thumb applies: "like dissolves like." Therefore:

  • For optimal solubility, non-polar solvents are preferred.
  • In contrast, polarity may limit solubility in aqueous environments, suggesting a poor solubility in water.

In summary, the solubility of 1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine is influenced by its structural components and the nature of the solvent, highlighting the fascinating interplay between chemical structure and solvent interactions.

Interesting facts

Interesting Facts about 1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine

1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine is a fascinating compound that combines the structural complexity of piperidine with the unique characteristics of a dioxolane moiety. This compound has drawn attention for several compelling reasons:

  • Versatile Applications: The incorporation of the piperidine ring enables this compound to exhibit varied biological activities, making it a valuable scaffold in drug design and medicinal chemistry.
  • Synthetic Interest: The synthesis of such compounds often involves intricate multi-step reactions that challenge chemists to develop innovative methodologies, contributing to advancements in organic synthesis.
  • Reactive Intermediates: The presence of the dioxolane unit can lead to interesting reactivity patterns, potentially allowing this compound to serve as a precursor for other important chemical species.
  • Structure-Activity Relationships: Researchers continually investigate the structure-activity relationships (SAR) of compounds like this, aiming to enhance their efficacy and reduce side effects, which is a critical endeavor in pharmacology.

In addition to its synthetic and biological significance, it is important to note that the compound's complexity also presents challenges in terms of characterization and stability. As highlighted by a prominent chemist, "Understanding the underlying properties of such multifaceted molecules is crucial for unlocking their full potential in research and application."

Overall, 1-benzyl-2-(2,2-diphenyl-1,3-dioxolan-4-yl)piperidine exemplifies the intersection of chemistry and innovation, serving as a testament to the continuous quest for new knowledge and the development of novel therapeutic agents.