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N-Benzylpiperazine

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Identification
Molecular formula
C17H25NO2
CAS number
2750-45-0
IUPAC name
(1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate
State
State

At room temperature, N-Benzylpiperazine is typically in a liquid state or can be observed as a white crystalline solid depending on the specific form and salt variation.

Melting point (Celsius)
36.00
Melting point (Kelvin)
309.15
Boiling point (Celsius)
425.20
Boiling point (Kelvin)
698.35
General information
Molecular weight
246.33g/mol
Molar mass
246.3310g/mol
Density
1.0698g/cm3
Appearence

N-Benzylpiperazine is a colorless liquid or white crystalline solid, often encountered in the form of its salt, commonly the dihydrochloride salt, which appears as a white powder.

Comment on solubility

Solubility Overview of (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate

The solubility of (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate is influenced by several key factors, including its molecular structure and the nature of solvents it encounters. Generally, the solubility of organic compounds like this acetate can be understood through the following considerations:

  • Polarity: Organic compounds often exhibit varying polarities. As (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate contains both polar and non-polar elements, it may show moderate solubility in polar solvents like water, but higher solubility in non-polar solvents.
  • Hydrogen Bonding: The presence of acetate functional groups, along with potential hydrogen bonding interactions, can enhance solubility in polar solvents.
  • Solvent-Solute Interactions: The compatibility of this compound with specific solvents greatly affects its solubility. For example, it may dissolve well in organic solvents such as ethanol or acetone due to favorable interactions.

It's also important to note that temperature can have a significant impact on solubility. Typically, an increase in temperature leads to a higher solubility for many compounds. Moreover, the "like dissolves like" principle serves as a fundamental guideline for predicting solubility characteristics:

  1. Non-polar solvents dissolve non-polar compounds.
  2. Polar solvents dissolve polar or ionic compounds.

In conclusion, while predicting the solubility of (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate can be complex, understanding its interacting components and the solvent environment is essential for a thorough evaluation.

Interesting facts

Interesting Facts about (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate

(1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate is a fascinating organic compound with a rich structural composition. This compound belongs to a class known as **acetates**, which are esters resulting from the reaction of acetic acid with an alcohol. Here are some intriguing points about this compound:

  • Unique Structure: The presence of a pyrrolidine ring fused with a propyl chain gives the compound distinct physical and chemical properties. The spiral configuration aids in its potential biological activity.
  • Benzyl and Methyl Substituents: The benzyl and methyl groups enhance the hydrophobic characteristics of the molecule. This makes it interesting in the study of interactions with biological membranes.
  • Potential Applications: Due to its structural features, this compound could have applications in medicinal chemistry, particularly in designing new pharmaceuticals targeting neurological disorders.
  • Research Subject: The compound may also serve as a model in academic chemistry to explore reaction mechanisms or the synthesis of more complex molecules.
  • Bioactivity Potential: There is growing interest in compounds containing pyrrolidine moieties as they may exhibit significant biological activity, including analgesic and antidepressant effects.

In summary, (1-benzyl-2-methyl-1-phenyl-3-pyrrolidin-1-yl-propyl) acetate is not just an ordinary compound; its intricate structure and potential applications make it a noteworthy subject in both organic chemistry and pharmacology. As researchers uncover its properties, we may find that this compound holds secrets critical for advancements in drug development.

Synonyms
Pyrrolifene
Pyrroliphene
15686-97-2
Pyrrolifene [INN]
pirrolifeno
UNII-T5Q0WA2589
T5Q0WA2589
1-Pyrrolidinepropanol, .beta.-methyl-.alpha.-phenyl-.alpha.-(phenylmethyl)-, acetate (ester)
pyrrolifenum
1-PYRROLIDINEPROPANOL, BETA-METHYL-ALPHA-PHENYL-ALPHA-(PHENYLMETHYL)-, ACETATE (ESTER)
xpsofsidlmrecy-uhfffaoysa-n
(3-methyl-1,2-diphenyl-4-pyrrolidin-1-ylbutan-2-yl) acetate
(+)-.alpha.-Benzyl-.beta.-methyl-.alpha.-phenyl-1-pyrrolidinepropanol acetate (ester)
SCHEMBL489016
CHEMBL2110705
DTXSID40935549
HY-U00081
AKOS040735905
CS-6620
DA-77265
NS00114100
Q27289704
1-Benzyl-2-methyl-1-phenyl-3-(1-pyrrolidinyl)propyl acetate #
3-Methyl-1,2-diphenyl-4-(pyrrolidin-1-yl)butan-2-yl acetate