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Metformin

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Identification
Molecular formula
C4H11N5
CAS number
1115-70-4
IUPAC name
1-benzyl-3-(diaminomethylene)-1-methyl-guanidine
State
State
Metformin is typically found as a solid at room temperature.
Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
129.16g/mol
Molar mass
129.1640g/mol
Density
1.3000g/cm3
Appearence
Metformin is a white to off-white crystalline solid with a bitter taste.
Comment on solubility

Solubility of 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine

The solubility of 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine can be influenced by several factors, including its chemical structure and the solvent used. This compound, rich in functional groups, has the potential for varied solubility characteristics.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar NH2 groups suggests that the compound might be soluble in polar solvents, such as water.
  • Size of the Benzyl Group: The bulky benzyl group can hinder solubility in certain solvents, but may enhance it in others.
  • Hydrogen Bonding: The ability to form hydrogen bonds can further increase solubility in polar environments.

In polar solvents, it is expected that this compound may exhibit reasonable solubility due to the favorable interactions between the polar functional groups and the solvent molecules. However, in non-polar solvents, the solubility would likely decrease due to the hydrophobic nature of the benzyl moiety.

In summary, while one can predict that 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine would be more soluble in polar solvents compared to non-polar ones, the exact solubility must be established through empirical tests.

Interesting facts

Interesting Facts about 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine

1-benzyl-3-(diaminomethylene)-1-methyl-guanidine is a fascinating compound that has garnered interest in various fields of research. Here are some highlights:

  • Pharmaceutical Applications: This compound has been studied for its potential use in pharmacology, particularly in developing drugs targeting certain receptor systems.
  • Research Significance: Its unique molecular structure allows for the exploration of novel pathways in chemical synthesis and biological activity.
  • Synthesis Opportunities: It can be synthesized through various methods, providing an excellent exercise in organic chemistry techniques.
  • Environmental Impact: Understanding its properties can help assess its environmental effects and stability in biological systems.
  • Biological Studies: There is ongoing research to explore how this compound interacts with biological mechanisms, particularly in disease models.

The guanidine moiety in this compound is particularly noteworthy. Guanidines are often recognized for their basicity and ability to form stable complexes with various ions, which can be valuable in medicinal chemistry.

Furthermore, the presence of the benzyl group enhances its pharmacological profiles by potentially improving solubility and biological activity. As one researcher noted, “The combination of unique structural features in 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine opens new avenues for exploration in drug design.”

In summary, 1-benzyl-3-(diaminomethylene)-1-methyl-guanidine is a compound that bridges organic chemistry and pharmaceutical science. Its unique chemical properties make it a topic of ongoing research and interest within the scientific community.

Synonyms
SCHEMBL14868311