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1-Benzyl-3-phenylazetidine

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Identification
Molecular formula
C16H17N
CAS number
25949-33-7
IUPAC name
1-benzyl-3-phenyl-azetidine
State
State

At room temperature, 1-Benzyl-3-phenylazetidine is in a liquid state. It is known for its stability in moderate conditions and can be handled in standard laboratory environments.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
331.50
Boiling point (Kelvin)
604.65
General information
Molecular weight
209.31g/mol
Molar mass
209.3110g/mol
Density
1.0667g/cm3
Appearence

1-Benzyl-3-phenylazetidine typically appears as a colorless to pale yellow liquid. It is an organic compound distinguished by its azetidine ring, which is a four-membered nitrogen-containing heterocycle.

Comment on solubility

Solubility of 1-benzyl-3-phenyl-azetidine

1-benzyl-3-phenyl-azetidine is a unique organic compound that exhibits distinct solubility characteristics. Its solubility can be summarized as follows:

  • Relatively Low Solubility: Generally, this compound has a low solubility in water due to the hydrophobic nature of the aromatic rings.
  • Solubility in Organic Solvents: It tends to dissolve well in non-polar organic solvents such as:
    • Hexane
    • Toluene
    • Dichloromethane
  • Temperature Dependence: The solubility can vary with temperature; as the temperature increases, solubility in organic solvents typically increases as well.

Furthermore, it is important to consider that the presence of substituents on the azetidine ring can influence the solubility characteristics. The electron-withdrawing or donating properties of these substituents may alter the overall polarity of the compound, thereby affecting its solubility profile.

As a general rule, "like dissolves like," meaning that the most favorable solubility will be observed when 1-benzyl-3-phenyl-azetidine is mixed with similar non-polar solvents. Consequently, careful attention must be paid to solvent selection in both laboratory and industrial applications to ensure optimal solubility characteristics.

Interesting facts

Exploring 1-benzyl-3-phenyl-azetidine

1-benzyl-3-phenyl-azetidine is a fascinating compound that belongs to the family of azetidines, which are four-membered nitrogen-containing cyclic compounds. What makes this compound particularly interesting is its structural uniqueness and potential applications in various fields of science.

Key Features

  • Cyclic Structure: The azetidine ring provides unique steric and electronic properties, making it an intriguing subject for synthetic chemists.
  • Pharmaceutical Potential: Compounds like 1-benzyl-3-phenyl-azetidine are being explored for their biological activities, with possible implications in drug design.
  • Diverse Reactions: Due to its structural characteristics, this compound can participate in a variety of chemical reactions, including nucleophilic substitutions and ring-opening reactions.

Applications and Research

The exploration of 1-benzyl-3-phenyl-azetidine in medicinal chemistry is particularly exciting. Scientists have noted that:

  • Its derivatives could potentially serve as lead compounds in developing anti-cancer drugs.
  • The compound’s unique nitrogen atom can interact with biological targets, making it an interesting candidate for further investigation.

As researchers continue to investigate the properties and potential of 1-benzyl-3-phenyl-azetidine, they aim to unlock new avenues in organic synthesis and medicinal applications. The future looks promising, and further studies may reveal even more exciting uses for this compound!

Synonyms
1-Benzyl-3-phenylazetidine
7215-16-9
AZETIDINE, 1-BENZYL-3-PHENYL-
L 2237
BRN 1428449
DTXSID60222483
DTXCID60144974
5-20-06-00284 (beilstein handbook reference)