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1-benzyl-3,4-dihydroisoquinoline

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Identification
Molecular formula
C16H15N
CAS number
22952-76-7
IUPAC name
1-benzyl-3,4-dihydroisoquinoline
State
State

At room temperature, 1-benzyl-3,4-dihydroisoquinoline is typically in a liquid state, particularly if the environment is slightly above standard room conditions. It may also crystallize to form a solid under certain conditions such as cooler temperatures.

Melting point (Celsius)
-15.00
Melting point (Kelvin)
258.15
Boiling point (Celsius)
331.00
Boiling point (Kelvin)
604.15
General information
Molecular weight
207.28g/mol
Molar mass
207.2750g/mol
Density
1.1508g/cm3
Appearence

1-benzyl-3,4-dihydroisoquinoline typically appears as a pale yellow liquid or solid, depending on the specific conditions such as temperature and purity. The compound's appearance can be crucial for identification in practical applications, including chemical synthesis and laboratory analysis.

Comment on solubility

Solubility of 1-benzyl-3,4-dihydroisoquinoline

1-benzyl-3,4-dihydroisoquinoline, a member of the isoquinoline family, exhibits interesting solubility characteristics. Understanding the solubility of this compound is essential for its applications in various fields.

Key Points About Solubility:

  • Solvent Type: Generally, 1-benzyl-3,4-dihydroisoquinoline is expected to be soluble in organic solvents such as ethanol, methanol, and chloroform, due to its non-polar characteristics.
  • Water Solubility: The solubility of this compound in water is limited, reflecting the trends of many organic compounds with larger hydrophobic regions.
  • Temperature Effect: Solubility can vary significantly with temperature; higher temperatures often enhance solubility in organic solvents.
  • pH Influence: The solubility may be influenced by the pH of the solvent, particularly if the compound has any ionizable functional groups.

As a result, when working with 1-benzyl-3,4-dihydroisoquinoline, it's important to choose the appropriate solvent for dissolution to maximize its utility in experimental settings. Understanding these solubility dynamics not only aids in preparation but also in the study of its reaction pathways and pharmacological properties.

Interesting facts

Interesting Facts about 1-benzyl-3,4-dihydroisoquinoline

1-benzyl-3,4-dihydroisoquinoline is a fascinating compound that showcases the intricate relationship between organic chemistry and medicinal applications. This compound belongs to the class of isoquinolines, which are bicyclic structures derived from benzene and pyridine. Here are some key highlights about this intriguing molecule:

  • Structural Significance: The unique combination of an isoquinoline core and a benzyl group makes this compound a versatile scaffold for various chemical modifications.
  • Biological Activity: Compounds similar to 1-benzyl-3,4-dihydroisoquinoline have been studied for their potential as antitumor agents, highlighting the importance of this structure in medicinal chemistry.
  • Synthesis: The synthesis of this compound can be achieved through several methods, including the Pictet-Spengler reaction, a classic route in organic synthesis, particularly noted for forming tetrahydroisoquinolines.
  • Pharmacological Potential: Research indicates that derivatives of isoquinoline structures may exhibit effects such as neuroprotective properties and anti-inflammatory activities.

In summary, 1-benzyl-3,4-dihydroisoquinoline represents a bridge between synthetic organic chemistry and advanced medicinal research. As the interplay of structure and biological activity continues to be explored, this compound exemplifies the innovation and applicability of chemical science across various fields.

Synonyms
24853-83-6
ISOQUINOLINE, 3,4-DIHYDRO-1-BENZYL-
DTXSID70179555
3,4-Dihydro-1-(phenylmethyl)isoquinoline
RefChem:1065741
DTXCID30102046
1-Benzyl-3,4-dihydroisoquinoline
Isoquinoline, 3,4-dihydro-1-(phenylmethyl)-
1-benzyl-3,4-dihydro-isoquinoline
BRN 0012064
AI3-61895
5-20-08-00290 (Beilstein Handbook Reference)
SCHEMBL5009247
CHEMBL4964090
SCHEMBL29757769
BQIIGTSQOCWPDH-UHFFFAOYSA-N
AKOS030605794
HS-8819
DB-378210
AE-562/12222520