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1-Benzyl-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C19H23NO2
CAS number
1814-30-0
IUPAC name
1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
State
State
At room temperature, it is typically a solid with a crystalline structure, often requiring specific storage conditions to maintain its stability and integrity for laboratory applications.
Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
383.20
Boiling point (Kelvin)
656.35
General information
Molecular weight
279.40g/mol
Molar mass
279.3690g/mol
Density
1.1050g/cm3
Appearence
1-Benzyl-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline appears as an off-white to pale yellow crystalline solid. It is typically synthesized for use in research contexts, particularly in the study of pharmacological agents.
Comment on solubility

Solubility of 1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

When assessing the solubility of 1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline, a few key aspects must be considered:

  • Solvent Dependent: The solubility of this compound can vary significantly depending on the solvent used, often showing higher solubility in organic solvents.
  • Polarity: Due to the presence of methoxy groups, the compound exhibits moderate polarity, influencing its solubility profile.
  • Hydrogen Bonding: The ability of methoxy groups to engage in hydrogen bonding can enhance solubility in polar solvents.

In general, this compound is expected to:

  • Be soluble in organic solvents such as ethyl acetate and chloroform.
  • Exhibit limited solubility in aqueous solutions due to its hydrophobic characteristics.

As a rule of thumb, one can say that the more polar the solvent, the more solubility is likely to increase for compounds with functional groups capable of hydrogen bonding. In summary, this isoquinoline derivative displays a unique solubility behavior that warrants further investigation in various solvent systems.

Interesting facts

Exploring 1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline is a fascinating organic compound that belongs to the isoquinoline class, which is known for its diverse biological activities. Here are some interesting facts about this particular compound:

  • Versatile Structure: The isoquinoline framework is a prominent structure in medicinal chemistry, serving as a scaffold for various bioactive compounds. This compound showcases an intricate arrangement of functional groups that enhance its reactivity and affinity for biological targets.
  • Potential Pharmacological Applications: Compounds containing isoquinoline structures have been researched for a variety of therapeutic effects, including analgesic, antitumor, and antimicrobial properties. This specific isoquinoline derivative may present similar bioactive profiles.
  • Natural Products Influence: Many isoquinolines are found in plant alkaloids, which contribute to the defense mechanisms of plants. Understanding this compound may lead to the discovery of new natural products or synthetic routes inspired by nature.
  • Synthetic Pathways: The synthesis of such complex compounds often involves multi-step processes, employing various reagents and conditions. This compound can serve as a case study in organic synthesis to illustrate how functional group manipulation can create diverse chemical entities.

As a chemist or a student, studying 1-benzyl-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline opens up avenues for understanding important concepts in structure-activity relationships, reaction mechanism, and the application of organic compounds in drug discovery. The exploration of this compound not only enriches our knowledge of chemical diversity but also has the potential to contribute to significant advances in pharmacology.

Synonyms
1-benzyl-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
SCHEMBL8236635
CHEMBL5274452
AK-105/40837640