1-Benzyloxy-2,3-diisopropyl-guanidine

Identification

Molecular formula

C₁₄H₂₆N₂O

CAS number

138803-51-9

IUPAC name

1-benzyloxy-2,3-diisopropyl-guanidine

State

This compound is typically found as a liquid at room temperature.

Melting point (Celsius)

-20.00

Melting point (Kelvin)

253.15

Boiling point (Celsius)

320.00

Boiling point (Kelvin)

593.15

General information

Molecular weight

236.37g/mol

Molar mass

236.3440g/mol

Density

1.0205g/cm³

Appearence

1-Benzyloxy-2,3-diisopropyl-guanidine typically appears as a colorless to pale yellow liquid. It may have a characteristic amine-like odor common to organic amine compounds.

Comment on solubility

Solubility of 1-Benzyloxy-2,3-diisopropyl-guanidine

The solubility of 1-benzyloxy-2,3-diisopropyl-guanidine in various solvents provides critical insights into its chemical behavior and potential applications. This compound exhibits the following characteristics regarding its solubility:

Solvent Dependence: Its solubility can vary significantly based on the polarity and nature of the solvent used.
Non-polar Solvents: It tends to be less soluble in non-polar solvents such as hexane and toluene due to the lack of favorable interactions.
Polar Solvents: Increased solubility is often observed in polar solvents such as ethanol and methanol, which can effectively stabilize the solute.
Aqueous Solubility: The presence of the guanidine functional group might enhance solubility in water, yet the overall hydrophobic diisopropyl and benzyloxy groups can limit its extent.

In conclusion, the solubility behavior of 1-benzyloxy-2,3-diisopropyl-guanidine is a complex interplay of its molecular structure and the intermolecular forces at work in various solvents. Understanding these solubility dynamics can significantly influence its practical applications in fields such as pharmaceuticals and chemical synthesis. As the saying goes, "Like dissolves like," highlighting the importance of molecular compatibility in solubility.

Interesting facts

Interesting Facts about 1-Benzyloxy-2,3-Diisopropyl-Guanidine

1-Benzyloxy-2,3-diisopropyl-guanidine is a fascinating compound that showcases the intricate world of organic chemistry. This compound is particularly notable for its unique structural features that contribute to its varied applications and potential in scientific research.

Key Features

Pharmacological Potential: Due to its guanidine core, this compound has been explored for potential therapeutic effects, particularly in the realm of neuropharmacology.
Organic Synthesis: The presence of the benzyloxy group can act as a protective group in organic synthesis, making it a versatile precursor in the formation of more complex molecules.
Steric Hindrance: The two isopropyl groups significantly influence the sterics of the compound, which can affect its reactivity and interaction with biological targets.

Research Significance

Researchers are particularly interested in this compound due to its ability to function as a modulator in various biological systems. Several studies have aimed to understand how modifications to the guanidine structure can lead to different bioactivities. The compound's potential in medicinal chemistry is further highlighted by its involvement in:

Enzyme inhibition studies
Development of therapeutic agents against neurological disorders
Exploratory research in drug design methodologies

A Note from Chemists

As stated by prominent chemists in the field, “The beauty of guanidine derivatives lies not just in their molecular structures, but in the rich tapestry of reactions they can undergo.” This statement certainly rings true for 1-benzyloxy-2,3-diisopropyl-guanidine, a compound that exemplifies the blend of simplicity and complexity inherent in organic synthesis.

Through continued study and exploration, 1-benzyloxy-2,3-diisopropyl-guanidine stands as a remarkable testament to the creativity and depth of the chemical sciences, opening doors for future innovations in drug discovery and development.