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1-Bromo-2-(trifluoromethyl)benzene

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Identification
Molecular formula
C7H4BrF3
CAS number
433-32-5
IUPAC name
1-bromo-2-(trifluoromethyl)benzene
State
State

At room temperature, 1-Bromo-2-(trifluoromethyl)benzene is a liquid.

Melting point (Celsius)
-1.00
Melting point (Kelvin)
272.15
Boiling point (Celsius)
181.50
Boiling point (Kelvin)
454.65
General information
Molecular weight
223.01g/mol
Molar mass
223.0070g/mol
Density
1.6590g/cm3
Appearence
1-Bromo-2-(trifluoromethyl)benzene is typically a colorless to pale yellow liquid.
Comment on solubility

Solubility of 1-bromo-2-(trifluoromethyl)benzene

1-bromo-2-(trifluoromethyl)benzene, with the chemical formula C8H5BrF3, exhibits distinct solubility characteristics primarily influenced by its chemical structure. As an organic compound containing halogens, it demonstrates the following solubility behavior:

  • Polar Solvents: Due to the presence of the electronegative fluorine atoms, 1-bromo-2-(trifluoromethyl)benzene exhibits some degree of polarity. However, the substantial hydrophobic aromatic ring reduces its overall solubility in water.
  • Non-Polar Solvents: This compound is more soluble in non-polar organic solvents such as hexane, benzene, and toluene. The aromatic character and the non-polar nature of the benzene ring promote favorable interactions with other non-polar molecules.
  • Temperature Dependency: Like many organic compounds, solubility can be temperature dependent; it may increase in certain non-polar solvents as temperature rises.

In summary, while 1-bromo-2-(trifluoromethyl)benzene is practically insoluble in water, it finds adequate solubility in various non-polar organic solvents. This behavior highlights the compound's hydrophobic characteristics, making it suitable for applications in organic synthesis and the study of hydrophobic interactions.

Interesting facts

Interesting Facts About 1-Bromo-2-(trifluoromethyl)benzene

1-Bromo-2-(trifluoromethyl)benzene is an intriguing aromatic compound with a unique structure, blending both bromine and trifluoromethyl functional groups. Here are some fascinating points about this compound:

  • General Structure: This compound is part of the phenyl halide family and consists of a bromine atom attached to a benzene ring, along with a trifluoromethyl group, which significantly influences its reactivity and properties.
  • Applications: The trifluoromethyl group enhances the compound's lipophilicity, making it useful in the synthesis of pharmaceuticals and agrochemicals. It serves as a valuable building block in organic synthesis.
  • Reactivity: The presence of both bromine and trifluoromethyl groups contributes to various chemical reactivity patterns, especially in electrophilic substitution reactions. The electron-withdrawing nature of the trifluoromethyl group can direct new substituents to specific positions on the benzene ring.
  • Biological Activity: Some derivatives of this compound have been studied for their potential biological activity, demonstrating the significance of aromatic halides in medicinal chemistry.
  • Environmental Concerns: As with many halogenated organic compounds, there are environmental considerations regarding their degradation and potential toxicity, making them a subject of research and regulation.

In summary, 1-bromo-2-(trifluoromethyl)benzene is not just a chemical formula; it represents a versatile compound with numerous applications in scientific research and industrial processes. This fascinating interplay between structure and function showcases the importance of understanding organic compounds in the field of chemistry.

Synonyms
2-Bromobenzotrifluoride
392-83-6
1-Bromo-2-(trifluoromethyl)benzene
o-Bromobenzotrifluoride
Benzene, 1-bromo-2-(trifluoromethyl)-
2-Bromo-alpha,alpha,alpha-trifluorotoluene
2-Brombenzotrifluorid
o-Bromobenzyltrifluoride
MFCD00000373
o-(Trifluoromethyl)bromobenzene
BRN 1945750
EINECS 206-879-9
2-Bromotrifluoromethylbenzene
2-(TRIFLUOROMETHYL)BROMOBENZENE
1-bromo-2-trifluoromethyl-benzene
o-Bromo(trifluoromethyl)benzene
DTXSID7059939
4-05-00-00831 (Beilstein Handbook Reference)
o-Bromo-.alpha.,.alpha.,.alpha.-trifluorotoluene
Toluene, o-bromo-.alpha.,.alpha.,.alpha.-trifluoro-
2-Brombenzotrifluorid [Czech]
Toluene, alpha,alpha,alpha-trifluoro-2-bromo-
bromobenzotrifluoride
2-bromo benzotrifluoride
trifluoromethylbromobenzene
o-bromotrifluoromethylbenzene
o-trifluoromethylbromobenzene
2-trifluoromethylbromobenzene
TOLUENE, o-BROMO-alpha,alpha,alpha-TRIFLUORO-
o-trifluoromethyl-bromobenzene
2-trifluoromethyl-bromobenzene
SCHEMBL363301
2-Bromobenzotrifluoride, 99%
o-bromo-a,a,a-trifluorotoluene
DTXCID4039605
1-bromo-2-trifluoromethylbenzene
2-Bromo-(trifluoromethyl)benzene
2-bromo-1-trifluoromethylbenzene
bromo-2-(trifluoromethyl)benzene
2-(trifluoromethyl)phenyl bromide
1-bromo-2-trifluoromethyl benzene
1-Bromo-2-(trifluoromethyl)benzene #
AKOS015853138
RP10155
AC-14089
AS-11984
o-Bromo-alpha,alpha,alpha-trifluorotoluene
2-bromo-I+/-,I+/-,I+/--trifluorotoluene
A6580
B0663
CS-0016026
NS00043153
EN300-65432
Toluene, .alpha.,.alpha.,.alpha.-trifluoro-2-bromo-
1-Bromo-2-(trifluoromethyl)benzene; o-Bromobenzotrifluoride