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1-Bromo-3-chloro-2-propanol

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Identification
Molecular formula
C3H6BrClO
CAS number
2933-93-9
IUPAC name
1-bromo-3-chloro-propan-2-ol
State
State

At room temperature, 1-Bromo-3-chloro-2-propanol is typically found in a liquid state. It has moderate viscosity and can be handled as a liquid for various applications.

Melting point (Celsius)
36.00
Melting point (Kelvin)
309.15
Boiling point (Celsius)
217.00
Boiling point (Kelvin)
490.15
General information
Molecular weight
175.45g/mol
Molar mass
175.4540g/mol
Density
1.7200g/cm3
Appearence

1-Bromo-3-chloro-2-propanol is a colorless to pale yellow liquid that may turn darker upon exposure to air or light. It has a viscous consistency and can exhibit a slight chloroform-like odor.

Comment on solubility

Solubility of 1-bromo-3-chloro-propan-2-ol

1-bromo-3-chloro-propan-2-ol, with the chemical formula C3H7BrClO, exhibits some notable characteristics regarding its solubility:

  • Polarity: The presence of both bromine and chlorine atoms along with the hydroxyl (–OH) group contributes to the compound's overall polarity, making it more likely to dissolve in polar solvents.
  • Solubility in Water: 1-bromo-3-chloro-propan-2-ol has limited solubility in water due to the bulky halogens which hinder interactions with water molecules, although the –OH group enhances its ability to engage in hydrogen bonding.
  • Miscibility with Organic Solvents: This compound is generally more soluble in organic solvents like ethanol and acetone, owing to similar polar characteristics.

As a point of reference, it is often said that “like dissolves like,” meaning compounds with similar polarities will tend to dissolve more effectively in one another. Therefore, while 1-bromo-3-chloro-propan-2-ol may not readily dissolve in water, it may find compatibility with various organic solvents, showcasing a fascinating interplay between structure and solubility.

Interesting facts

Interesting Facts about 1-bromo-3-chloro-propan-2-ol

1-bromo-3-chloro-propan-2-ol is a fascinating compound that serves as an important intermediate in various chemical syntheses. Here are some intriguing facts about this versatile molecule:

  • Dual Halogenation: The presence of both bromine and chlorine atoms in its structure enhances its reactivity, making it a valuable building block in organic synthesis.
  • Functional Group Diversity: This compound contains both alcohol and halogen functional groups. This feature allows it to participate in a wide array of reactions, such as substitution and elimination processes.
  • Applications in Pharmaceuticals: Compounds like 1-bromo-3-chloro-propan-2-ol are often used in the development of pharmaceutical agents, particularly as precursors for more complex medicinal molecules.
  • Chiral Center: With its chiral carbon atom, this compound can exist in different stereoisomeric forms. This chirality is significant since the activity of different isomers can vary dramatically in biological systems.

As a chemist, it's essential to appreciate the nuanced roles such compounds play in research and industry. They embody the complexities and interconnected nature of chemistry, where simple variations can lead to profound implications in functional properties and applications.

In terms of safety, handling and storing compounds like 1-bromo-3-chloro-propan-2-ol requires caution due to the potential hazards associated with halogenated organic compounds. Always ensure proper laboratory protocols are followed!

In conclusion, while 1-bromo-3-chloro-propan-2-ol may seem like just another halogenated alcohol, its properties and applications highlight the beautiful intricacies that define the world of chemistry.

Synonyms
1-Bromo-3-chloropropan-2-ol
1-BROMO-3-CHLORO-2-PROPANOL
EINECS 224-891-2
NSC 173177
DTXSID301310623
DTXCID601021136
2-Propanol, 1-bromo-3-chloro-(8CI)
2-Propanol, 1-bromo-3-chloro-(8CI)(9CI)
224-891-2
4540-44-7
2-Propanol, 1-bromo-3-chloro-
MFCD07783144
NSC173177
starbld0037098
SCHEMBL4246254
TVDCSPSRGSLXOV-UHFFFAOYSA-N
ALBB-032330
AKOS006282543
NSC-173177
1-Bromo-3-chloro-2-propanol, 96 %
LS-11961
DS-002773
NS00048715
G78808