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1-Bromo-3-iodobenzene

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Identification
Molecular formula
C6H4BrI
CAS number
591-18-4
IUPAC name
1-bromo-3-iodo-benzene
State
State

At room temperature, 1-bromo-3-iodobenzene is in a solid state.

Melting point (Celsius)
27.00
Melting point (Kelvin)
300.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
282.90g/mol
Molar mass
282.8940g/mol
Density
2.0705g/cm3
Appearence

1-Bromo-3-iodobenzene is typically observed as a colorless to pale yellow solid. It is an aromatic compound, and the presence of bromine and iodine substituents gives it a distinct halogenated aromatic odor.

Comment on solubility

Solubility of 1-bromo-3-iodo-benzene

1-bromo-3-iodo-benzene, with the chemical formula C6H4BrI, exhibits intriguing solubility characteristics. Being a halogenated aromatic compound, its solubility can be influenced by several factors:

  • Polarity: The presence of both bromo (Br) and iodo (I) substituents adds some degree of polarity, though the overall molecule remains mainly nonpolar due to the aromatic nature.
  • Solvent Type: 1-bromo-3-iodo-benzene is more soluble in organic solvents such as acetone, diethyl ether, and benzene. However, it has limited solubility in polar solvents like water.
  • Temperature Influence: Increasing temperature generally enhances solubility in organic solvents, allowing for better dissolution of the compound.

In summary, while 1-bromo-3-iodo-benzene shows significant solubility in organic solvents, its limited solubility in water illustrates the general trend for halogenated aromatic compounds. The interplay of functional groups and molecular structure is crucial in determining the solubility behavior of such compounds.

Interesting facts

Interesting Facts About 1-Bromo-3-iodo-benzene

1-bromo-3-iodo-benzene, a fascinating aromatic compound, is widely studied for its unique properties and potential applications in organic synthesis. This compound exhibits a rich combination of halogen substituents which contribute to its reactivity, making it an essential target in the field of medicinal chemistry and materials science.

Key Features

  • Halogen Substitution: The presence of both bromine and iodine in the aromatic ring enhances the compound's ability to participate in various electrophilic substitutions, paving the way for complex organic transformations.
  • Synthetic Versatility: Due to its reactivity, it can serve as a precursor to various biologically active compounds, allowing chemists to explore new pathways for drug discovery.
  • Research Applications: Due to its halogenated nature, it is valuable in studies aimed at understanding the effects of halogens on biological systems and chemical reactivity.

Historical and Practical Significance

This compound is not only of academic interest but also finds utility in practical applications:

  • Drug Development: Compounds like 1-bromo-3-iodo-benzene are often explored for their potential as pharmaceuticals, exhibiting antimicrobial and anti-inflammatory properties.
  • Materials Science: It has implications in the development of new materials where halogen functionalities can enhance properties such as thermal stability and solubility.

In the words of chemists, “Every halogen on an aromatic ring has a story to tell.” 1-bromo-3-iodo-benzene is a vivid example of how halogen substitution can dramatically alter the behavior and utility of organic molecules, making them invaluable in both research and applications.

Synonyms
1-BROMO-3-IODOBENZENE
591-18-4
Benzene, 1-bromo-3-iodo-
EINECS 209-703-9
DTXSID9060447
DTXCID0042539
209-703-9
3-Bromoiodobenzene
m-Bromoiodobenzene
3-bromo-1-iodobenzene
MFCD00001043
1-iodo-3-bromobenzene
MQH7NC2UMH
1-bromo-3-iodo-benzene
m-Bromjodbenzol
3-iodobromobenzene
3-bromo iodobenzene
3-iodo-bromobenzene
UNII-MQH7NC2UMH
1-bromo-3-iodo benzene
1-bromo-5-iodo-benzene
3-Bromo-1-iodo-benzene
3-Bromoiodobenzene, 98%
SCHEMBL79244
1-bromanyl-3-iodanyl-benzene
AKOS005254502
CS-W008957
GS-3094
PB47618
HY-32149
SY005126
DB-013829
B1236
NS00034089
EN300-114507
P15297
A832168
Z381540820
InChI=1/C6H4BrI/c7-5-2-1-3-6(8)4-5/h1-4