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N-Butylpyrrolidone

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Identification
Molecular formula
C8H15NO
CAS number
3470-98-2
IUPAC name
1-butylpyrrolidin-2-one
State
State

N-Butylpyrrolidone is a liquid at room temperature. It is widely used in industrial applications due to its solvent properties and ease of handling in its liquid state.

Melting point (Celsius)
-77.00
Melting point (Kelvin)
196.20
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.20
General information
Molecular weight
141.21g/mol
Molar mass
141.2120g/mol
Density
0.9817g/cm3
Appearence

N-Butylpyrrolidone is a colorless to pale yellow liquid. It has a characteristic amine-like odor. It is corrosive and hygroscopic, meaning it readily absorbs water from the environment. Its liquid form allows it to be easily mixed with water and organic solvents, making it a versatile solvent for various applications.

Comment on solubility

Solubility of 1-butylpyrrolidin-2-one

1-butylpyrrolidin-2-one, also known as butyrolactam, is a compound characterized by its unique structure which influences its solubility profile. This compound is generally recognized for its good solubility in numerous organic solvents. Below are notable points regarding the solubility of 1-butylpyrrolidin-2-one:

  • Solvents: It is soluble in polar organic solvents such as ethanol, acetone, and dichloromethane.
  • Aqueous Solubility: It tends to have limited solubility in water due to its non-ionic nature, making it more amenable to organic rather than aqueous solutions.
  • Temperature Dependency: Solubility can increase with temperature, typically making higher temperatures favorable for dissolving this compound in organic solvents.

As a general statement, compounds like 1-butylpyrrolidin-2-one, with their relatively lipophilic characteristics and the presence of polar functional groups, illustrate a trend where the solubility is higher in non-polar or moderately polar environments. Understanding the solubility of such compounds is crucial for applications in fields such as pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about 1-Butylpyrrolidin-2-one

1-Butylpyrrolidin-2-one is an intriguing compound that belongs to the class of pyrrolidinones, notable for its versatile applications in various fields of chemistry. Here are some fascinating points that highlight the significance and utility of this compound:

  • Solvent Properties: This compound is often utilized as a solvent due to its ability to dissolve a wide range of polar and non-polar substances, making it valuable in industrial processes.
  • Intermediate in Synthesis: 1-Butylpyrrolidin-2-one serves as an important intermediate in the synthesis of various bioactive molecules and pharmaceuticals. Its structure allows for further derivatization, which can lead to the generation of novel compounds with potential therapeutic effects.
  • Exciting Applications: Beyond its role in synthesis, it is also employed in the development of coatings, adhesives, and polymers due to its chemical stability and efficiency at facilitating reactions.
  • Research Interest: This compound has attracted the attention of researchers studying the structure-activity relationship (SAR) in medicinal chemistry. Its unique properties and functionalities promote valuable insights into designing better pharmaceuticals.
  • Safety Considerations: While it shows great promise, it is important to handle this compound with care, as appropriate safety measures must be taken to mitigate any potential risks associated with its use.

The study of 1-butylpyrrolidin-2-one illustrates the intersection of organic chemistry and practical applications, representing the importance of chemical innovation in addressing real-world challenges. As scientists continue to explore its potential, this compound may pave the way for further discoveries in medicinal and industrial chemistry.

Synonyms
1-Butylpyrrolidin-2-one
3470-98-2
1-Butyl-2-pyrrolidinone
2-PYRROLIDINONE, 1-BUTYL-
N-Butylpyrrolidone
N-Butylpyrrolidinone
N-Butyl-2-pyrrolidone
BRN 0111543
EINECS 222-437-8
DTXSID80188254
EC 222-437-8
DTXCID10110745
222-437-8
1-Butyl-2-pyrrolidone
1-N-Butyl-2-Pyrrolidone
N-Butyl-2-pyrrolidinone
MFCD00020876
1-Butyl-2-pyrrolidione
N-n-Butyl-2-pyrrolidone
N-Butyl-2-azacyclopentanone
SCHEMBL10513
BCP24378
AKOS006228803
AB01298
CS-W016436
AC-24510
AS-36941
FB159395
SY020373
DB-337165
B1254
NS00010159
EN300-7414036