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ThioTEPA hydrochloride

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Identification
Molecular formula
C7H14Cl3NO2
CAS number
6525-65-1
IUPAC name
1-carboxyethyl-bis(2-chloroethyl)ammonium;chloride
State
State

The compound is typically a solid at room temperature. Due to its hygroscopic nature, it should be stored in a moisture-free environment to maintain its integrity.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.00
Boiling point (Celsius)
349.00
Boiling point (Kelvin)
622.00
General information
Molecular weight
322.60g/mol
Molar mass
322.6000g/mol
Density
1.4150g/cm3
Appearence

ThioTEPA hydrochloride appears as a crystalline powder that is white to off-white in color. It is hygroscopic and should be handled with care to avoid moisture absorption.

Comment on solubility

Solubility of 1-carboxyethyl-bis(2-chloroethyl)ammonium;chloride

The solubility of 1-carboxyethyl-bis(2-chloroethyl)ammonium;chloride can be quite intriguing due to its unique chemical structure. This compound, containing both ammonium and chloride ions, exhibits some distinctive solubility characteristics:

  • Water Solubility: It is generally expected that quaternary ammonium salts, like this one, are highly soluble in water owing to their ionic nature. The presence of the −Cl− ion helps in stabilizing the ion-dipole interactions with water molecules.
  • Organic Solvents: The solubility in organic solvents may vary. Depending on the solvent polarity, its solubility can be moderate to low. Polar aprotic solvents may enhance solubility due to interactions with the charged ammonium group.
  • Temperature Dependence: The solubility may also be influenced by temperature. An increase in temperature usually enhances solubility for ionic compounds; thus, higher temperatures could facilitate its dissolution.

In practical applications, understanding the solubility is crucial, especially in scenarios involving biological activity and industrial processes. As with many compounds, the solubility not only determines its utility but also plays a significant role in its properties and behavior in various environments.

As noted in various studies, the solubility characteristics of this compound can lead to interesting interactions in biological systems, highlighting the importance of solubility in chemical science.

Interesting facts

Interesting Facts about 1-Carboxyethyl-bis(2-chloroethyl)ammonium Chloride

1-Carboxyethyl-bis(2-chloroethyl)ammonium chloride is a fascinating compound that belongs to a class of chemicals known for their diverse applications in various fields. Here are some notable aspects of this compound:

  • Biological Relevance: As a quaternary ammonium compound, it exhibits interesting biological properties that can be harnessed in medicinal chemistry.
  • Chemical Reactivity: The presence of chlorinated ethyl groups indicates potential reactivity with nucleophiles, making this compound a candidate for further chemical transformations.
  • Applications in Materials Science: Compounds like this one can be utilized in synthesizing polymers with antimicrobial properties, which are valuable in coatings and textiles.
  • Potential in Drug Development: Researchers are exploring similar ammonium compounds for their potential as pharmaceuticals due to their ability to interact with biological membranes.

In essence, 1-carboxyethyl-bis(2-chloroethyl)ammonium chloride serves as a testament to the intricate interplay between structure and function in chemistry. As a part of ongoing research, it's exciting to think about how compounds like this can pave the way for innovations in health and materials technology. As noted by chemists, “the potential lies in understanding how modification of one group can lead to vastly different properties.”

Synonyms
Alanine mustard
NSC 17663
2752-21-8
ALANINE, N,N-BIS(2-CHLOROETHYL)-, HYDROCHLORIDE, DL-
3374-04-7
N,N'-Bis(2-chloroethyl)alanine hydrochloride
ALANINE, N,N'-BIS(2-CHLOROETHYL)-, HYDROCHLORIDE
AI3-50855
N,N-Bis(beta-chloroethyl) DL-alanine hydrochloride
N,N-Bis(beta-chloroethyl)d,l-alanine hydrochloride
N,N-Bis(beta-chloroethyl)-D,L-alanine hydrochloride