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1-Chloro-2-fluorobenzene

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Identification
Molecular formula
C6H4ClF
CAS number
348-51-6
IUPAC name
1-chloro-2-fluoro-benzene
State
State

At room temperature, 1-Chloro-2-fluorobenzene is in a liquid state.

Melting point (Celsius)
-13.00
Melting point (Kelvin)
260.15
Boiling point (Celsius)
155.60
Boiling point (Kelvin)
428.75
General information
Molecular weight
128.56g/mol
Molar mass
128.5560g/mol
Density
1.2370g/cm3
Appearence

1-Chloro-2-fluorobenzene is a clear, colorless liquid. It typically exhibits a slight aromatic odor, typical of halogenated aromatic compounds.

Comment on solubility

Solubility of 1-chloro-2-fluoro-benzene

1-chloro-2-fluoro-benzene, with the chemical formula C6H4ClF, exhibits specific solubility characteristics that are noteworthy for understanding its behavior in various solvents.

Solubility characteristics include:

  • Polar solvents: 1-chloro-2-fluoro-benzene shows limited solubility in water due to its primarily non-polar character.
  • Non-polar solvents: It is more soluble in organic solvents such as hexane and ether, aligning with its non-polar attributes.
  • Solvent interactions: The presence of chlorine and fluorine atoms contributes to the molecule's ability to engage in dipole-dipole interactions with polar solvents, although these interactions are not strong enough to facilitate significant solubility.

As a rule of thumb in organic chemistry, “like dissolves like” holds true. Therefore, non-polar solvents will typically dissolve 1-chloro-2-fluoro-benzene more effectively than polar ones. This property makes it a valuable compound in various chemical applications, particularly those necessitating non-polar environments.

Interesting facts

Interesting Facts about 1-Chloro-2-fluoro-benzene

1-Chloro-2-fluoro-benzene is a fascinating compound within the group of halogenated aromatic hydrocarbons. Here are some intriguing aspects to consider:

  • Structure and Isomerism: This compound exhibits an interesting molecular structure, characterized by the presence of both a chlorine (Cl) and a fluorine (F) atom on the benzene ring. The positioning of these halogens makes it a member of a larger family of derivatives, leading to various isomeric forms.
  • Reactivity: The presence of halogens in aromatics like 1-chloro-2-fluoro-benzene often alters their reactivity. These compounds can participate in electrophilic aromatic substitution reactions, making them valuable intermediates in organic synthesis.
  • Applications: This compound plays a significant role in the synthesis of pharmaceuticals and agrochemicals. Its unique properties are harnessed in various applications, including as a precursor in the production of more complex molecules.
  • Environmental Impact: As with many halogenated compounds, there is ongoing research into the environmental fate of 1-chloro-2-fluoro-benzene. Understanding its degradation pathways is crucial for assessing potential ecological risks.
  • Human Health Considerations: Scientists are also interested in the toxicity and health implications of exposure to this compound. Proper handling and understanding of safety protocols are essential in laboratory and industrial settings.

In summary, 1-chloro-2-fluoro-benzene is not just a simple aromatic compound; its unique properties and potential applications make it a subject of interest in both academic and industrial chemistry. As we explore its various facets, we gain insight into the broader applications of halogenated compounds in modern science.

Synonyms
1-CHLORO-2-FLUOROBENZENE
348-51-6
2-Chlorofluorobenzene
o-Chlorofluorobenzene
Benzene, 1-chloro-2-fluoro-
o-Fluorochlorobenzene
1-Fluoro-2-chlorobenzene
1-chloro-2-fluoro-benzene
NSC 10270
CHLOROFLUOROBENZENE
EINECS 206-476-8
DTXSID8059841
NSC-10270
Benzene, chlorofluoro-
2-FLUOROCHLOROBENZENE
oChlorofluorobenzene
oFluorochlorobenzene
1Fluoro2chlorobenzene
ortho-chlorofluorobenzene
Benzene, 1chloro2fluoro
JUQ2V3V2AA
SCHEMBL168042
DTXCID1038903
1-Chloro-2-fluorobenzene, 98%
1-Chloro-2-fluorobenzene, 99%
NSC10270
MFCD00000533
AKOS005063959
DS-1906
A6119
NS00042080
EN300-20293
A20498
M-Chlorofluorobenzene;1-chloro-3-fluoro-benzen
206-476-8