Skip to main content

1-Chloro-2,4-dimethoxy-5-nitrobenzene

ADVERTISEMENT
Identification
Molecular formula
C8H8ClNO4
CAS number
73847-57-1
IUPAC name
1-chloro-2,4-dimethoxy-5-nitro-benzene
State
State

State at room temperature: Solid

This compound is typically found in a solid state due to its relatively high melting point above typical room temperatures.

Melting point (Celsius)
53.00
Melting point (Kelvin)
326.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
217.59g/mol
Molar mass
217.5940g/mol
Density
1.3380g/cm3
Appearence

1-Chloro-2,4-dimethoxy-5-nitrobenzene appears as a yellow crystalline solid. It is not hygroscopic and has a distinct nitroaromatic odor typical to nitro compounds.

Comment on solubility

Solubility of 1-chloro-2,4-dimethoxy-5-nitro-benzene

1-chloro-2,4-dimethoxy-5-nitro-benzene, known for its complex structure, exhibits specific solubility characteristics that are influenced by its functional groups and overall polarity. Here are the key points regarding its solubility:

  • Polarity: The presence of polar functional groups like nitro (–NO2) and methoxy (–OCH3) can enhance solubility in polar solvents.
  • Solvent Compatibility: This compound is generally soluble in organic solvents like ethanol, methanol, and acetone due to its ability to engage in dipole-dipole interactions.
  • Insolubility in Water: Due to its relatively large aromatic structure and chlorinated group, 1-chloro-2,4-dimethoxy-5-nitro-benzene is typically insoluble or poorly soluble in water, a characteristic common among many aromatic compounds.
  • Temperature Effects: Solubility can also vary with temperature; increased temperatures may enhance solubility in specific organic solvents.

In conclusion, understanding the solubility of 1-chloro-2,4-dimethoxy-5-nitro-benzene is essential for its practical applications in chemical processes, as it dictates the choice of solvents and reaction conditions. Always consider the specific surroundings and intended usage when assessing the solubility of this compound.

Interesting facts

Interesting Facts About 1-chloro-2,4-dimethoxy-5-nitro-benzene

1-chloro-2,4-dimethoxy-5-nitro-benzene is a fascinating compound due to its unique structure and versatile applications. Here are some noteworthy aspects:

  • Substituted Benzene: This compound is classified as a substituted benzene and features various functional groups including a chloro, nitro, and methoxy group. Each group contributes to the compound's reactivity and behavior in chemical reactions.
  • Importance in Synthesis: It serves as a valuable intermediate in organic synthesis, especially in the production of more complex chemicals and pharmaceuticals. The presence of both electron-withdrawing and electron-donating groups makes it a suitable candidate for electrophilic aromatic substitution reactions.
  • Pharmaceutical Applications: Compounds with similar structures are often investigated for their potential biological activities. Researchers are particularly interested in the anti-cancer and anti-inflammatory properties that may arise from such nitro-substituted compounds.
  • Colorful Nature: The nitro group’s electron-withdrawing effect can impact the electronic properties of the molecule, often leading to interesting spectroscopic features that make it a subject of study for chemists using techniques such as UV-Vis spectroscopy.
  • Safety and Handling: As with many nitro compounds, safety considerations are paramount. It is essential to handle this compound with care due to the potential risks associated with nitro groups, which can sometimes be explosive under certain conditions.

In summary, 1-chloro-2,4-dimethoxy-5-nitro-benzene encapsulates a blend of structural intrigue and practical utility in the field of chemistry, making it an engaging topic for chemists and students alike.

Synonyms
1-Chloro-2,4-dimethoxy-5-nitrobenzene
119-21-1
5-Chloro-2,4-dimethoxynitrobenzene
BENZENE, 1-CHLORO-2,4-DIMETHOXY-5-NITRO-
XNE3D7GP2S
Benzene, 5-chloro-1-nitro-2,4-dimethoxy-
EINECS 204-306-7
NSC 50662
BRN 2331671
NSC-50662
DTXSID7059482
4-06-00-05694 (Beilstein Handbook Reference)
2,4-DIMETHOXY-5-CHLORONITROBENZENE
NSC50662
Benzene,1-chloro-2,4-dimethoxy-5-nitro-
UNII-XNE3D7GP2S
Benzene,4-dimethoxy-5-nitro-
WLN: WNR CG DO1 FO1
DTXCID6033459
SCHEMBL11661312
MFCD00024316
AKOS023552894
1-Chloro-2,4-dimethoxy-5-nitrobenzene #
DS-006752
CS-0150480
NS00023842
E76534
204-306-7